Risk factors for late relapse in male and female ex-smokers.

Three hundred twenty-nine ex-smokers (149 males and 180 females) who had maintained abstinence for at least 3 months prior to intake were followed for a period of 1 year to ascertain individual characteristics from cognitive, behavioral, environmental, and health domains that were predictive of later relapse. Multiple logistic regression analysis revealed significant associations between relapse, family history, and stress variables in males and between relapse, family history, stress, pre- and postcessation smoking characteristics, work-related variables, and physical activity in females. Within the predictor sets, both risk and protective factors were identified. The male and female models are discussed separately, compared, and related to previous research. Implications for further model development are specified; most notably, the utility of conceptualizing relapse independent of gender is questioned. Future research efforts could focus on the role played by family smoking history in adult relapse behavior. Smoking cessation interventions may need to tailor their efforts specifically to men and to women. Along with techniques to manage stress both during and after cessation, women may benefit especially from interventions that provide nicotine replacement and counseling for work-related difficulties.