| Literature DB >> 31770128 |
Danny S Lee1,2, Jessica E Hann1,3, Sukhpreet S Klaire1, Mohammadali Nikoo4, Michael D Negraeff5, Pouya Rezazadeh-Azar1,6,7,8,9.
Abstract
Buprenorphine is an effective treatment for chronic pain and may reduce opioid-induced hyperalgesia. However, its pharmacological properties make its induction challenging, time-consuming, and can precipitate opioid withdrawal. We present the case of a 66-year-old woman with inadequately controlled postoperative pain despite escalating doses of oxycodone and methadone, who was successfully transitioned to buprenorphine/naloxone using a rapid microinduction technique without precipitating opioid withdrawal. Rapid induction provides an alternative method for transitioning patients from other opioids to buprenorphine/naloxone and facilitates transition of patients with chronic pain to buprenorphine therapy within a shorter window compared to currently existing protocols.Entities:
Mesh:
Substances:
Year: 2020 PMID: 31770128 PMCID: PMC7147949 DOI: 10.1213/XAA.0000000000001138
Source DB: PubMed Journal: A A Pract ISSN: 2575-3126