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Literature DB >> 31769017

Genomic foundations of evolution and ocular pathogenesis in human adenovirus species D.

Ashrafali Mohamed Ismail¹, Xiaohong Zhou¹, David W Dyer², Donald Seto³, Jaya Rajaiya¹, James Chodosh¹.

Abstract

Human adenovirus commonly causes infections of respiratory, gastrointestinal, genitourinary, and ocular surface mucosae. Although most adenovirus eye infections are mild and self-limited, specific viruses within human adenovirus species D are associated with epidemic keratoconjunctivitis (EKC), a severe and highly contagious ocular surface infection, which can lead to chronic and/or recurrent, visually disabling keratitis. In this review, we discuss the links between adenovirus ontogeny, genomics, immune responses, and corneal pathogenesis, for those viruses that cause EKC.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: conjunctivitis; epidemic keratoconjunctivitis; genomics; homologous recombination; human adenovirus; inflammation; ocular infection; pink eye; tropism; virus evolution

Mesh：

Substances：

Year: 2019 PMID： 31769017 PMCID： PMC7185199 DOI： 10.1002/1873-3468.13693

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

257 in total

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11 in total

1. RANBP2 and USP9x regulate nuclear import of adenovirus minor coat protein IIIa.

Authors: Ashrafali M Ismail; Amrita Saha; Ji S Lee; David F Painter; Yinghua Chen; Gurdeep Singh; Gabriela N Condezo; James Chodosh; Carmen San Martín; Jaya Rajaiya
Journal: PLoS Pathog Date: 2022-06-16 Impact factor: 7.464

2. Molecular and Clinical Characterization of Human Adenovirus E4-Associated Conjunctivitis.

Authors: Russell N Van Gelder; Lakshmi Akileswaran; Kenji Nakamichi; David Stroman
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3. The FDA-Approved Drug Nelfinavir Inhibits Lytic Cell-Free but Not Cell-Associated Nonlytic Transmission of Human Adenovirus.

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Review 4. Adenovirus and the Cornea: More Than Meets the Eye.

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Review 5. Exploring the potential of foodborne transmission of respiratory viruses.

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Review 6. Human Adenovirus Species D Interactions with Corneal Stromal Cells.

Authors: Jaya Rajaiya; Amrita Saha; Xiaohong Zhou; James Chodosh
Journal: Viruses Date: 2021-12-14 Impact factor: 5.048

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Journal: Viruses Date: 2020-05-04 Impact factor: 5.048