Annekatrin Rickmann1, Christoph Andres2, Karl Boden2, Silke Wahl2, Peter Szurman2,3. 1. Eye Clinic Sulzbach, Knappschaft Hospital Saar, An der Klinik 10, 66280, Sulzbach/Saar, Germany. annekatrin.rickmann@kksaar.de. 2. Eye Clinic Sulzbach, Knappschaft Hospital Saar, An der Klinik 10, 66280, Sulzbach/Saar, Germany. 3. Centre for Ophthalmology, University Eye Clinic Tuebingen, Tuebingen, Germany.
Abstract
PURPOSE: The purpose of this study is to compare the safety and clinical results of descemet membrane endothelial keratoplasty (DMEK) in topical, peribulbar or general anesthesia. METHODS: This is a retrospective, post hoc matched study of 120 patients having received DMEK surgery with different types of anesthesia (n = 40 topical, n = 40 peribulbar, n = 40 general anesthesia). Endpoint criteria were intraoperative complications, endothelial cell count, central corneal thickness and graft rejection rate, rebubbling rate and best-corrected visual acuity after 1, 3 and 6 months. RESULTS: The group with topical anesthesia showed more often intraoperative difficulties such as vitreous pressure (p < 0.05), difficult graft unfolding (p = 0.14) and patient restlessness (p = 0.07). However, all three groups achieved comparable functional visual results after 6 months (p = 0.96). CONCLUSION: DMEK in topical anesthesia is feasible and shows comparable final visual results but should be restricted to selected cooperative patients and performed by experienced surgeons due to possible higher intraoperative challenges.
PURPOSE: The purpose of this study is to compare the safety and clinical results of descemet membrane endothelial keratoplasty (DMEK) in topical, peribulbar or general anesthesia. METHODS: This is a retrospective, post hoc matched study of 120 patients having received DMEK surgery with different types of anesthesia (n = 40 topical, n = 40 peribulbar, n = 40 general anesthesia). Endpoint criteria were intraoperative complications, endothelial cell count, central corneal thickness and graft rejection rate, rebubbling rate and best-corrected visual acuity after 1, 3 and 6 months. RESULTS: The group with topical anesthesia showed more often intraoperative difficulties such as vitreous pressure (p < 0.05), difficult graft unfolding (p = 0.14) and patient restlessness (p = 0.07). However, all three groups achieved comparable functional visual results after 6 months (p = 0.96). CONCLUSION: DMEK in topical anesthesia is feasible and shows comparable final visual results but should be restricted to selected cooperative patients and performed by experienced surgeons due to possible higher intraoperative challenges.
Authors: Sonia N Yeung; Peter Kim; Alejandro Lichtinger; Maoz D Amiran; Simon Hollands; Sabrina Teitel; Max A Levitt; Allan R Slomovic Journal: Int Ophthalmol Date: 2012-03-24 Impact factor: 2.031
Authors: Annekatrin Rickmann; Peter Szurman; Sacha Jung; Karl Thomas Boden; Silke Wahl; Arno Haus; Katrin Boden; Kai Januschowski Journal: Curr Eye Res Date: 2018-01-29 Impact factor: 2.424
Authors: Alba Gómez-Benlloch; Maximiliano Olivera; Jeroni Nadal; Gemma Julio; Javier Elizalde Journal: Int J Ophthalmol Date: 2022-10-18 Impact factor: 1.645
Authors: Mukhtar Bizrah; Geoffrey Ching; Ammar M Yusuf; Nizar Din; Sonia N Yeung; James Martin McCarthy; Alfonso Iovieno; Simon P Holland Journal: Eye (Lond) Date: 2021-07-09 Impact factor: 4.456