Literature DB >> 31768363

Patient-Reported Outcomes and Quality of Life after Treatment for Choroidal Melanoma.

Bertil Damato1,2, Laura Hope-Stone2, Bruce Cooper1, Steve Brown2, Heinrich Heimann2, Laura Dunn3.   

Abstract

BACKGROUND/AIMS: Patients with choroidal melanoma can develop psychological morbidity because of visual disability, pain, facial deformity, and fears of metastatic disease. The aim of this study was to report on the prevalence of symptoms, moods, and well-being after radiotherapy or enucleation for choroidal melanoma and how these outcomes changed over time.
METHODS: Participants were mailed questionnaires approximately 6 months following treatment, then annually on every anniversary of their treatment.
RESULTS: Soon after enucleation, patients experienced visual difficulties because of loss of stereopsis and visual field and were concerned about their appearance and about metastatic disease. After radiotherapy, patients were more concerned about local tumor recurrence and more troubled by diplopia and headache. Over time, visual difficulties diminished after enucleation but increased in patients who had received radiotherapy, with concerns about metastasis, loss of health, and tumor recurrence diminishing in both groups. Anxiety tended to diminish whereas depression increased, especially after enucleation. Emotional well-being improved after both kinds of treatment, whereas functional and physical well-being diminished after enucleation but improved after radiotherapy. Self-reported quality of life diminished equally with both kinds of treatment.
CONCLUSION: The findings of this study should help physicians understand what patients tend to feel after treatment for choroidal melanoma.
Copyright © 2019 by S. Karger AG, Basel.

Entities:  

Keywords:  Anxiety; Choroidal melanoma; Depression; Enucleation; Quality of life; Radiotherapy; Well-being

Year:  2019        PMID: 31768363      PMCID: PMC6873060          DOI: 10.1159/000496927

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  15 in total

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2.  Ambulatory cancer and US general population reference values and cutoff scores for the functional assessment of cancer therapy.

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3.  Treatment choice and quality of life in patients with choroidal melanoma.

Authors:  K J Cruickshanks; D G Fryback; D M Nondahl; N Robinson; U Keesey; D S Dalton; D M Robertson; S R Chandra; W F Mieler; Z N Zakov; P L Custer; L V Del Priore; D M Albert
Journal:  Arch Ophthalmol       Date:  1999-04

Review 4.  Estimating prognosis for survival after treatment of choroidal melanoma.

Authors:  Bertil Damato; Antonio Eleuteri; Azzam F G Taktak; Sarah E Coupland
Journal:  Prog Retin Eye Res       Date:  2011-05-30       Impact factor: 21.198

5.  Taping outpatient consultations: a survey of attitudes and responses of adult patients with ocular malignancy.

Authors:  F G Ah-Fat; M C Sharma; B E Damato
Journal:  Eye (Lond)       Date:  1998       Impact factor: 3.775

6.  Patient-reported Outcomes and Quality of Life After Treatment of Choroidal Melanoma: A Comparison of Enucleation Versus Radiotherapy in 1596 Patients.

Authors:  Bertil Damato; Laura Hope-Stone; Bruce Cooper; Steve L Brown; Peter Salmon; Heinrich Heimann; Laura B Dunn
Journal:  Am J Ophthalmol       Date:  2018-03-17       Impact factor: 5.258

7.  The hospital anxiety and depression scale.

Authors:  A S Zigmond; R P Snaith
Journal:  Acta Psychiatr Scand       Date:  1983-06       Impact factor: 6.392

8.  Quality of life after iodine 125 brachytherapy vs enucleation for choroidal melanoma: 5-year results from the Collaborative Ocular Melanoma Study: COMS QOLS Report No. 3.

Authors:  Michele Melia; Claudia S Moy; Sandra M Reynolds; James A Hayman; Timothy G Murray; Kenneth R Hovland; John D Earle; Natalie Kurinij; Li Ming Dong; Päivi H Miskala; Connie Fountain; David Cella; Carol M Mangione
Journal:  Arch Ophthalmol       Date:  2006-02

9.  Influence of uveal melanoma therapy on patients' quality of life: a psychological study.

Authors:  Sophie Chabert; Michaela Velikay-Parel; Martin Zehetmayer
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10.  The Patient's Experience of Ocular Melanoma in the US: A Survey of the Ocular Melanoma Foundation.

Authors:  Armin R Afshar; Michael Deiner; Grant Allen; Bertil E Damato
Journal:  Ocul Oncol Pathol       Date:  2018-02-08
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Authors:  R N Hussain; B Damato; H Heimann
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3.  Improving the quality of life of patients undergoing enucleation.

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4.  Prognostic and Functional Analysis of NPY6R in Uveal Melanoma Using Bioinformatics.

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