PURPOSE: The objective of this study ws to describe the quality of life of 98 patients treated with brachytherapy or stereotactic external beam irradiation, either with the Leksell Gamma Knife or a 6-MV LINAC. METHODS: The EORTC QLQ-C30 and the EORTC QLQ-OPT37 psychological questionnaires and the HADS-D scale were used. Two visual analogue scales (VASs) were applied to compare overall quality of life before and after treatment. RESULTS: The results revealed no significant differences in quality of life (p=0.215) among treatments with different methods of radiotherapy. Comparison of quality of life before and after therapy did, however, indicate a decrease in quality of following radiotherapy. The average binocular visual acuity (VA) was 0.8 (range 0.3-1). Complication arising from the treatment included a reduction in VA in the affected eye, keratitis, cataract, scleral and corneal necrosis, radiation retinopathy, radiation optic neuropathy, retinal detachment and glaucoma. CONCLUSIONS: Due to the diagnosis revealed and the subsequent radiotherapy, patients with uveal melanoma experienced a reduced quality of life. However, compared to patients with other types of cancer, they seemed to feel relatively well and showed fewer signs of deterioration.
PURPOSE: The objective of this study ws to describe the quality of life of 98 patients treated with brachytherapy or stereotactic external beam irradiation, either with the Leksell Gamma Knife or a 6-MV LINAC. METHODS: The EORTC QLQ-C30 and the EORTC QLQ-OPT37 psychological questionnaires and the HADS-D scale were used. Two visual analogue scales (VASs) were applied to compare overall quality of life before and after treatment. RESULTS: The results revealed no significant differences in quality of life (p=0.215) among treatments with different methods of radiotherapy. Comparison of quality of life before and after therapy did, however, indicate a decrease in quality of following radiotherapy. The average binocular visual acuity (VA) was 0.8 (range 0.3-1). Complication arising from the treatment included a reduction in VA in the affected eye, keratitis, cataract, scleral and corneal necrosis, radiation retinopathy, radiation optic neuropathy, retinal detachment and glaucoma. CONCLUSIONS: Due to the diagnosis revealed and the subsequent radiotherapy, patients with uveal melanoma experienced a reduced quality of life. However, compared to patients with other types of cancer, they seemed to feel relatively well and showed fewer signs of deterioration.
Authors: Johannes Gollrad; Christopher Rabsahl; Antonia M Joussen; Andrea Stroux; Volker Budach; Dirk Böhmer; Alexander Böker Journal: Ocul Oncol Pathol Date: 2021-11-08
Authors: A Klingenstein; C Fürweger; A K Mühlhofer; S F Leicht; U C Schaller; A Muacevic; B Wowra; C Hintschich; K H Eibl Journal: Graefes Arch Clin Exp Ophthalmol Date: 2015-11-16 Impact factor: 3.117
Authors: Christopher A Barker; Anna Kozlova; Alexander N Shoushtari; Jennifer L Hay; Jasmine H Francis; David H Abramson Journal: Ocul Oncol Pathol Date: 2019-09-27
Authors: Jennifer van Dijk; Saskia M Imhof; Annette C Moll; Peter J Ringens; Peggy T Cohen-Kettenis; Frank Rijmen; Jaap Huisman Journal: Health Qual Life Outcomes Date: 2007-06-04 Impact factor: 3.186