| Literature DB >> 31767749 |
Lennard C van der Woude1, Giorgio Perrella2,3, Basten L Snoek4, Mark van Hoogdalem5, Ondřej Novák6,7, Marcel C van Verk4,8, Heleen N van Kooten1, Lennert E Zorn1, Rolf Tonckens1, Joram A Dongus1, Myrthe Praat1, Evelien A Stouten1, Marcel C G Proveniers1, Elisa Vellutini2, Eirini Patitaki2, Umidjon Shapulatov5, Wouter Kohlen9, Sureshkumar Balasubramanian10, Karin Ljung6, Alexander R van der Krol5, Sjef Smeekens1, Eirini Kaiserli2, Martijn van Zanten11.
Abstract
Many plant species respond to unfavorable high ambient temperatures by adjusting their vegetative body plan to facilitate cooling. This process is known as thermomorphogenesis and is induced by the phytohormone auxin. Here, we demonstrate that the chromatin-modifying enzyme HISTONE DEACETYLASE 9 (HDA9) mediates thermomorphogenesis but does not interfere with hypocotyl elongation during shade avoidance. HDA9 is stabilized in response to high temperature and mediates histone deacetylation at the YUCCA8 locus, a rate-limiting enzyme in auxin biosynthesis, at warm temperatures. We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with YUCCA8, allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis.Entities:
Keywords: Arabidopsis; H2A.Z; HDA9; shade avoidance; thermomorphogenesis
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Year: 2019 PMID： 31767749 PMCID： PMC6911240 DOI： 10.1073/pnas.1911694116
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205