Antonino Tuttolomondo1, Domenico Di Raimondo2, Alessandra Casuccio3, Mariachiara Velardo2, Giovanni Salamone2, Marco Cataldi2, Francesca Corpora2, Vincenzo Restivo3, Rosaria Pecoraro4, Vittoriano Della Corte5, Carlo Maida2, Irene Simonetta2, Anna Cirrincione2, Valerio Vassallo2, Antonio Pinto2. 1. Internal Medicine and Stroke Care Ward, Department of Promoting Health, Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo, Italy. Electronic address: bruno.tuttolomondo@unipa.it. 2. Internal Medicine and Stroke Care Ward, Department of Promoting Health, Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo, Italy. 3. Department of Promoting Health, Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo, Italy. 4. IRCCS Centro Neurolesi Bonino Pulejo, Palermo, Italy. 5. Molecular and Clinical Medicine, University of Palermo, Palermo, Italy.
Abstract
OBJECTIVES: To our knowledge, no study has addressed the relationship between adherence to a Mediterranean diet style and severity of heart failure. The aim of this retrospective study was to evaluate the relationship between adherence to the Mediterranean diet assessed using the calculation of Mediterranean diet score and congestive heart failure (CHF), its severity, and pathogenesis. METHODS: We analyzed charts and collected data of all consecutive patients with a diagnosis of CHF at admission to our Internal Medicine Ward from 2008 to 2014. RESULTS: We analyzed 209 patients with CHF and 200 controls. Patients with CHF showed a significantly lower mean MeDi score than controls. At receiver operating characteristic curve analysis, we found a good sensitivity and specificity of mean MeDi score to predict CHF. We also observed a significant positive correlation between MeDi score and ischemic pathogenesis of CHF, a positive relationship between New York Heart Association (NYHA) class and ischemic heart disease, and a significant negative relationship between NYHA class and MeDi score. CONCLUSION: The beneficial effects of adherence to the Mediterranean diet suggest a possible answer to the question of the biochemical bases of our data, which should be seen as the direct consequence of the anti-inflammatory, antioxidant, and anti-remodeling effects linked to the diet.
OBJECTIVES: To our knowledge, no study has addressed the relationship between adherence to a Mediterranean diet style and severity of heart failure. The aim of this retrospective study was to evaluate the relationship between adherence to the Mediterranean diet assessed using the calculation of Mediterranean diet score and congestive heart failure (CHF), its severity, and pathogenesis. METHODS: We analyzed charts and collected data of all consecutive patients with a diagnosis of CHF at admission to our Internal Medicine Ward from 2008 to 2014. RESULTS: We analyzed 209 patients with CHF and 200 controls. Patients with CHF showed a significantly lower mean MeDi score than controls. At receiver operating characteristic curve analysis, we found a good sensitivity and specificity of mean MeDi score to predict CHF. We also observed a significant positive correlation between MeDi score and ischemic pathogenesis of CHF, a positive relationship between New York Heart Association (NYHA) class and ischemic heart disease, and a significant negative relationship between NYHA class and MeDi score. CONCLUSION: The beneficial effects of adherence to the Mediterranean diet suggest a possible answer to the question of the biochemical bases of our data, which should be seen as the direct consequence of the anti-inflammatory, antioxidant, and anti-remodeling effects linked to the diet.
Authors: Jibran A Wali; Natalia Jarzebska; David Raubenheimer; Stephen J Simpson; Roman N Rodionov; John F O'Sullivan Journal: Nutrients Date: 2020-05-21 Impact factor: 5.717
Authors: Domenico Di Raimondo; Gaia Musiari; Giuliana Rizzo; Edoardo Pirera; Salvatore Santo Signorelli Journal: Int J Environ Res Public Health Date: 2022-02-21 Impact factor: 3.390
Authors: Salvatore Ficarra; Domenico Di Raimondo; Giovanni Angelo Navarra; Mohammad Izadi; Alessandra Amato; Francesco Paolo Macaluso; Patrizia Proia; Gaia Musiari; Carola Buscemi; Anna Maria Barile; Cristiana Randazzo; Antonino Tuttolomondo; Silvio Buscemi; Marianna Bellafiore Journal: J Pers Med Date: 2022-07-28