Literature DB >> 31754926

Effect of Synthetic Organoselenium Drug on the Degree of Pathological Changes in the Organs of White Mice Immunized with Tularemia and Brucellosis Vaccines.

O V Yurieva1, V I Dubrovina2, V A Potapov3, M V Musalov3, T P Starovoitova1, T A Ivanova1, A V Gromova1, T T Shkaruba1, S V Balakhonov1.   

Abstract

We studied the effect of the organoselenium compound 2,6-dipyridinium-9-selenium-bicyclo[ 3,3,1]nonan dibromide (974zh) on the severity of pathological changes in the organs of experimental animals immunized with live tularemia and brucellosis vaccines. It was found that 974zh reduced reactogenicity of vaccines for experimental animals. Our findings indicate the prospects for further studies of the effects of 974zh on the functional state of experimental animals.

Entities:  

Keywords:  Brucella abortus; Francisella tularensis; degree of pathological changes in organs; organoselenium compound; vaccine

Mesh：

Substances：

Year:  2019        PMID： 31754926     DOI： 10.1007/s10517-019-04648-0

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  2 in total

1.  Effect of a Synthetic Organoselenium Compound on Post-Vaccination Immunopoiesis in the Red Bone Marrow and Cell Composition of Peripheral Blood of White Mice Vaccinated with Yersinia pestis EV.

Authors:  V I Dubrovina; T P Starovoitova; O V Yur'eva; A B Pyatidesyatnikova; V A Potapov; M V Musalov; S V Balakhonov
Journal:  Bull Exp Biol Med       Date:  2021-10-07       Impact factor: 0.804

2.  Efficient Synthesis of a New Family of 2,6-Disulfanyl-9-selenabicyclo[3.3.1]nonanes.

Authors:  Maxim V Musalov; Vladimir A Potapov; Svetlana V Amosova
Journal:  Molecules       Date:  2021-05-11       Impact factor: 4.411
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.