Literature DB >> 31753184

The Science and (Lost) Art of Psoralen Plus UVA Phototherapy.

Elisabeth G Richard1.   

Abstract

PUVA phototherapy is the therapeutic use of psoralens and UVA light to treat inflammatory skin diseases, with psoriasis the prototype disease. Naturally occurring phototoxic compounds, psoralens interact with UVA to suppress DNA synthesis and cell proliferation and induce apoptosis of inflammatory cells. Well-developed therapeutic protocols for psoriasis guide psoralen and UVA doses, treatment frequency, and safety measures, and these protocols also may be used to treat other inflammatory dermatoses.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Dermatitis; PUVA; Photochemotherapy; Psoralen; Psoriasis; Vitiligo

Mesh：

Substances：

Year:  2019        PMID： 31753184     DOI： 10.1016/j.det.2019.08.002

Source DB:  PubMed          Journal:  Dermatol Clin        ISSN： 0733-8635            Impact factor:   3.478


  3 in total

Review 1.  Extracorporeal Photopheresis in Graft-versus-Host Disease.

Authors:  Beatrice Drexler; Andreas Buser; Laura Infanti; Gregor Stehle; Joerg Halter; Andreas Holbro
Journal:  Transfus Med Hemother       Date:  2020-05-19       Impact factor: 3.747

2.  Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.

Authors:  Yuhao Wang; Yonglun Wang; Fang Li; Jie Zou; Xiaoqian Li; Mengxia Xu; Daojiang Yu; Yijia Ma; Wei Huang; Xiaodong Sun; Yuanyuan Zhang
Journal:  Cells       Date:  2022-03-22       Impact factor: 6.600

3.  Novel psoralen derivatives as anti-breast cancer agents and their light-activated cytotoxicity against HER2 positive breast cancer cells.

Authors:  Chiphada Aekrungrueangkit; Sirilak Wangngae; Anyanee Kamkaew; Ruchuta Ardkhean; Sanit Thongnest; Jutatip Boonsombat; Somsak Ruchirawat; Tanatorn Khotavivattana
Journal:  Sci Rep       Date:  2022-08-05       Impact factor: 4.996
  3 in total

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