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Literature DB >> 31746809

C. Ronald Kahn: The Louisville Slugger of metabolic science.

Jeffrey S Flier.

Abstract

Mesh：

Substances：
Insulin

Year: 2019 PMID： 31746809 PMCID： PMC6877302 DOI： 10.1172/JCI133156

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

× No keyword cloud information.

15 in total

1. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Authors: R N Kulkarni; J C Brüning; J N Winnay; C Postic; M A Magnuson; C R Kahn
Journal: Cell Date: 1999-02-05 Impact factor: 41.582

2. Role of brain insulin receptor in control of body weight and reproduction.

Authors: J C Brüning; D Gautam; D J Burks; J Gillette; M Schubert; P C Orban; R Klein; W Krone; D Müller-Wieland; C R Kahn
Journal: Science Date: 2000-09-22 Impact factor: 47.728

3. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

Authors: E Araki; M A Lipes; M E Patti; J C Brüning; B Haag; R S Johnson; C R Kahn
Journal: Nature Date: 1994-11-10 Impact factor: 49.962

4. Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome.

Authors: Siegfried Ussar; Nicholas W Griffin; Olivier Bezy; Shiho Fujisaka; Sara Vienberg; Samir Softic; Luxue Deng; Lynn Bry; Jeffrey I Gordon; C Ronald Kahn
Journal: Cell Metab Date: 2015-08-20 Impact factor: 27.287

5. Direct demonstration that receptor crosslinking or aggregation is important in insulin action.

Authors: C R Kahn; K L Baird; D B Jarrett; J S Flier
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

6. Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host-microbe interactions.

Authors: Emrah Altindis; Weikang Cai; Masaji Sakaguchi; Fa Zhang; Wang GuoXiao; Fa Liu; Pierre De Meyts; Vasily Gelfanov; Hui Pan; Richard DiMarchi; C Ronald Kahn
Journal: Proc Natl Acad Sci U S A Date: 2018-02-21 Impact factor: 11.205

Review 2. Is type 2 diabetes an adiposity-based metabolic disease? From the origin of insulin resistance to the concept of dysfunctional adipose tissue.

Authors: Paolo Sbraccia; Monica D'Adamo; Valeria Guglielmi
Journal: Eat Weight Disord Date: 2021-02-08 Impact factor: 4.652

2 in total

C. Ronald Kahn: The Louisville Slugger of metabolic science.

1. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

2. Role of brain insulin receptor in control of body weight and reproduction.

3. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

4. Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome.

5. Direct demonstration that receptor crosslinking or aggregation is important in insulin action.

6. Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host-microbe interactions.

7. Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance.

8. Extended longevity in mice lacking the insulin receptor in adipose tissue.

9. Positional cloning of the mouse obese gene and its human homologue.

10. Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor.

Review 1. The insulin receptor family in the heart: new light on old insights.

Review 2. Is type 2 diabetes an adiposity-based metabolic disease? From the origin of insulin resistance to the concept of dysfunctional adipose tissue.