Helena Garcez1, Carina Fernandes1, Fernando Barbosa1, Mariana R Pereira1, Celeste Silveira1,2, João Marques-Teixeira1, Ana R Gonçalves3. 1. Laboratory of Neuropsychophysiology, Faculty of Psychology and Education Sciences, University of Porto, Rua Alfredo Allen, 4200-135, Porto, Portugal. 2. São João University Hospital Center, Porto, Portugal. 3. Laboratory of Neuropsychophysiology, Faculty of Psychology and Education Sciences, University of Porto, Rua Alfredo Allen, 4200-135, Porto, Portugal. anasgoncalves@fpce.up.pt.
Abstract
RATIONALE: Benzodiazepines, a class of commonly prescribed drugs, were shown to cause cognitive impairments in several domains. However, the effect of benzodiazepines on social cognition is still unclear. OBJECTIVES: In order to clarify how benzodiazepines administration affects the identification of facial expressions of emotion (FEE), we conducted a meta-analysis of 8 empirical studies (N = 153 benzodiazepines, N = 153 placebo). RESULTS: Results showed that participants receiving benzodiazepines were less accurate at identifying facial expressions of anger compared with those receiving placebo (M = - 0.52). Regarding the remaining facial expressions, the meta-analysis did not reveal significant differences between the groups. CONCLUSIONS: We discuss several factors that may explain the differences in the identification of emotions in facial expressions associated with benzodiazepines administration. Additionally, the relevance of assessing the effects of benzodiazepines when used on a long-term basis is addressed.
RATIONALE: Benzodiazepines, a class of commonly prescribed drugs, were shown to cause cognitive impairments in several domains. However, the effect of benzodiazepines on social cognition is still unclear. OBJECTIVES: In order to clarify how benzodiazepines administration affects the identification of facial expressions of emotion (FEE), we conducted a meta-analysis of 8 empirical studies (N = 153 benzodiazepines, N = 153 placebo). RESULTS: Results showed that participants receiving benzodiazepines were less accurate at identifying facial expressions of anger compared with those receiving placebo (M = - 0.52). Regarding the remaining facial expressions, the meta-analysis did not reveal significant differences between the groups. CONCLUSIONS: We discuss several factors that may explain the differences in the identification of emotions in facial expressions associated with benzodiazepines administration. Additionally, the relevance of assessing the effects of benzodiazepines when used on a long-term basis is addressed.
Entities:
Keywords:
Benzodiazepines; Emotion identification; Facial expressions; Performance; Social cognition
Authors: Cristina M Del-Ben; Cesar A Q Ferreira; Tiago A Sanchez; Wolme C Alves-Neto; Vinicius G Guapo; Draulio B de Araujo; Frederico G Graeff Journal: J Psychopharmacol Date: 2010-11-24 Impact factor: 4.153