Literature DB >> 31739275

Meta-analytic approaches for examining complexity and heterogeneity in studies of adolescent development.

Nicholas J Parr1, Maria L Schweer-Collins2, Todd M Darlington3, Emily E Tanner-Smith2.   

Abstract

INTRODUCTION: In the field of adolescent development, meta-analysis offers valuable tools for synthesizing and assessing cumulative research evidence on the effectiveness of programs, practices, and policies intended to promote healthy adolescent development. When examining the impact of a program implemented across multiple primary studies, variation is often observed in the methodological attributes of those primary studies, such as their implementation methods, program components, participant characteristics, outcome measurement, and the systems in which programs are deployed. Differences in methodological attributes of primary studies represented in a meta-analysis, referred to as complexity, can yield variation in true effects across primary studies, which is described as heterogeneity.
METHODS: We discuss heterogeneity as a parameter of interest in meta-analysis, introducing and demonstrating both graphical and statistical methods for evaluating the magnitude and impact of heterogeneity. We discuss approaches for presenting characteristics of heterogeneity in meta-analytic findings, and methods for identifying and statistically controlling for aspects of methodological complexity that may contribute to variation in effects across primary studies.
RESULTS: Topics and methods related to assessing and explaining heterogeneity were contextualized in the field of adolescent development using a sample of primary studies from a large meta-analysis examining the effectiveness of brief alcohol interventions for youth. We highlighted approaches currently underutilized in the field and provided R code for key methods to broaden their use.
CONCLUSIONS: By discussing various heterogeneity statistics, visualizations, and explanatory methods, this article provides the applied developmental researcher a foundational understanding of complexity and heterogeneity in meta-analysis.
Copyright © 2019 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Heterogeneity; Meta-analysis; Meta-regression; Methodological complexity; R

Mesh:

Year:  2019        PMID: 31739275      PMCID: PMC6934259          DOI: 10.1016/j.adolescence.2019.10.009

Source DB:  PubMed          Journal:  J Adolesc        ISSN: 0140-1971


  34 in total

Review 1.  Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses.

Authors:  D Moher; D J Cook; S Eastwood; I Olkin; D Rennie; D F Stroup
Journal:  Lancet       Date:  1999-11-27       Impact factor: 79.321

2.  Quantifying heterogeneity in a meta-analysis.

Authors:  Julian P T Higgins; Simon G Thompson
Journal:  Stat Med       Date:  2002-06-15       Impact factor: 2.373

Review 3.  Interventions for reducing adolescent alcohol abuse: a meta-analytic review.

Authors:  Stephen J Tripodi; Kimberly Bender; Christy Litschge; Michael G Vaughn
Journal:  Arch Pediatr Adolesc Med       Date:  2010-01

Review 4.  Understanding heterogeneity in meta-analysis: the role of meta-regression.

Authors:  W L Baker; C Michael White; J C Cappelleri; J Kluger; C I Coleman
Journal:  Int J Clin Pract       Date:  2009-10       Impact factor: 2.503

5.  Using multiple group modeling to test moderators in meta-analysis.

Authors:  Alexander M Schoemann
Journal:  Res Synth Methods       Date:  2016-12       Impact factor: 5.273

6.  The prevention of depressive symptoms in children and adolescents: A meta-analytic review.

Authors:  Jason L Horowitz; Judy Garber
Journal:  J Consult Clin Psychol       Date:  2006-06

Review 7.  Why sources of heterogeneity in meta-analysis should be investigated.

Authors:  S G Thompson
Journal:  BMJ       Date:  1994-11-19

8.  A meta-analysis of after-school programs that seek to promote personal and social skills in children and adolescents.

Authors:  Joseph A Durlak; Roger P Weissberg; Molly Pachan
Journal:  Am J Community Psychol       Date:  2010-06

Review 9.  Brief alcohol interventions for adolescents and young adults: a systematic review and meta-analysis.

Authors:  Emily E Tanner-Smith; Mark W Lipsey
Journal:  J Subst Abuse Treat       Date:  2014-09-16

10.  Commentary: Heterogeneity in meta-analysis should be expected and appropriately quantified.

Authors:  Julian P T Higgins
Journal:  Int J Epidemiol       Date:  2008-10       Impact factor: 7.196

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  2 in total

Review 1.  Effects of brief substance use interventions delivered in general medical settings: a systematic review and meta-analysis.

Authors:  Emily E Tanner-Smith; Nicholas J Parr; Maria Schweer-Collins; Richard Saitz
Journal:  Addiction       Date:  2021-10-14       Impact factor: 6.526

2.  Using Machine Learning to Identify and Investigate Moderators of Alcohol Use Intervention Effects in Meta-Analyses.

Authors:  Nicholas J Parr; Christopher M Loan; Emily E Tanner-Smith
Journal:  Alcohol Alcohol       Date:  2022-01-08       Impact factor: 3.913

  2 in total

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