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Literature DB >> 31738397

Antibiotic Duration, but Not Abscess Size, Impacts Clinical Cure of Limited Skin and Soft Tissue Infection After Incision and Drainage.

Jason G Lake¹, Loren G Miller², Stephanie A Fritz¹.

Abstract

Antibiotics are frequently prescribed following incision and drainage of cutaneous abscesses. In subgroup analyses from a recent clinical trial, we observed higher likelihood of cure with antibiotic courses beyond 5 or 7 days (up to 10). Among this cohort, for abscesses ≤5 cm, size did not modify the antibiotic effect.

Keywords: SSTI; adjunctive antibiotic; clindamycin; incision and drainage; trimethoprim-sulfamethoxazole

Year: 2020 PMID： 31738397 PMCID： PMC7384315 DOI： 10.1093/cid/ciz1129

Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079

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References

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Antibiotic Duration, but Not Abscess Size, Impacts Clinical Cure of Limited Skin and Soft Tissue Infection After Incision and Drainage.

1. Preferred treatment and prevention strategies for recurrent community-associated methicillin-resistant Staphylococcus aureus skin and soft-tissue infections: a survey of adult and pediatric providers.

2. A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses.

3. Trimethoprim-Sulfamethoxazole Therapy Reduces Failure and Recurrence in Methicillin-Resistant Staphylococcus aureus Skin Abscesses after Surgical Drainage.

4. Board-certified emergency physicians' treatment of skin and soft tissue infections in the community-acquired methicillin-resistant Staphylococcus aureus era.

5. Variability among pediatric infectious diseases specialists in the treatment and prevention of methicillin-resistant Staphylococcus aureus skin and soft tissue infections.

6. Subgroup Analysis of Antibiotic Treatment for Skin Abscesses.

7. Impact of Systemic Antibiotics on Staphylococcus aureus Colonization and Recurrent Skin Infection.

8. Incidence of skin and soft tissue infections in ambulatory and inpatient settings, 2005-2010.

9. Clinical management of skin and soft tissue infections in the U.S. Emergency Departments.