Literature DB >> 31735700

The Basic Physics of Waves, Soundwaves, and Shockwaves for Erectile Dysfunction.

Jonathan Elliott Katz1, Raul Ivan Clavijo2, Paul Rizk1, Ranjith Ramasamy3.   

Abstract

INTRODUCTION: Over the past decade, low-intensity extracorporeal shockwave therapy (Li-ESWT) has emerged as a treatment modality for erectile dysfunction (ED). To better appreciate the differences between the various devices for the treatment of ED, it is imperative for physicians to understand the underlying physics of the different shockwave generators. AIM: In this article, we explain the physics of shockwaves by establishing a foundation regarding the basics of waves, specifically soundwaves. We also describe the different shockwave generators available and assess their potential clinical utility.
METHODS: We reviewed basic principles of wave propagation, randomized controlled trials investigating Li-ESWT for ED and other medical diseases, and individual industry shockwave generator websites, in order to describe the basic physics underlying Li-ESWT. MAIN OUTCOME MEASURE: We primarily aimed to describe the physics underlying shockwave generators and to provide a framework for understanding the relevant subtypes and adjustable parameters.
RESULTS: A wave is a disturbance in a medium that transports energy without permanently transporting matter. In shockwaves, a soundwave is generated with a speed faster than the local speed of sound. Shockwaves are classically generated by three different types of energy sources: electrohydraulic, electromagnetic, or piezoelectric, which all create a shockwave through the conversion of electric potential energy to mechanical energy. Importantly, radial pressure waves do not behave the same as conventional shockwaves and are more like "ordinary" sound waves in that they achieve a significantly lower peak pressure, a slower rise time, and propagate outwards without a focal point. CLINICAL IMPLICATIONS: Li-ESWT is not currently approved by the U.S. Food and Drug Administration and is considered investigational in the United States. However, it is currently available to patients under clinical trial protocols and it is important to understand the basic physics of shockwaves to understand the differences between the different shockwave devices. STRENGTH & LIMITATIONS: This is a comprehensive review of the physics underlying Li-ESWT but only tangentially explores the biological impact of shockwaves.
CONCLUSION: Physicians currently using or those contemplating purchasing a Li-ESWT device should understand the basic physics underlying the device, as well as which treatment protocols were used to demonstrate clinical efficacy in treating ED. Katz JE, Clavijo RI, Rizk P, et al. The Basic Physics of Waves, Soundwaves, and Shockwaves for Erectile Dysfunction. Sex Med Rev 2020;8:100-105.
Copyright © 2019 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Erectile Dysfunction; Extracorporeal Shockwave Therapy; Low-Intensity Extracorporeal Shockwave Therapy (Li-ESWT)

Year:  2019        PMID: 31735700      PMCID: PMC6934904          DOI: 10.1016/j.sxmr.2019.09.004

Source DB:  PubMed          Journal:  Sex Med Rev        ISSN: 2050-0521


  15 in total

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Journal:  Int J Immunopathol Pharmacol       Date:  2006 Jan-Mar       Impact factor: 3.219

2.  Does low intensity extracorporeal shock wave therapy have a physiological effect on erectile function? Short-term results of a randomized, double-blind, sham controlled study.

Authors:  Yoram Vardi; Boaz Appel; Amichai Kilchevsky; Ilan Gruenwald
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Review 3.  Low-intensity Extracorporeal Shock Wave Treatment Improves Erectile Function: A Systematic Review and Meta-analysis.

Authors:  Zhihua Lu; Guiting Lin; Amanda Reed-Maldonado; Chunxi Wang; Yung-Chin Lee; Tom F Lue
Journal:  Eur Urol       Date:  2016-06-16       Impact factor: 20.096

Review 4.  Effects of Low-Intensity Extracorporeal Shockwave Therapy on Erectile Dysfunction: A Systematic Review and Meta-Analysis.

Authors:  Raul I Clavijo; Taylor P Kohn; Jaden R Kohn; Ranjith Ramasamy
Journal:  J Sex Med       Date:  2016-12-13       Impact factor: 3.802

Review 5.  Low-Intensity Shockwave Therapy for Erectile Dysfunction.

Authors:  Paul J Rizk; Jordan R Krieger; Taylor P Kohn; Alexander W Pastuszak
Journal:  Sex Med Rev       Date:  2018-03-22

6.  The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction: A Systematic Scoping Review of Pre-Clinical Studies.

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7.  Low intensity extracorporeal shockwave therapy for erectile dysfunction: a study in an Indian population.

Authors:  Vasan Satya Srini; Rahul Kumar Reddy; Tamar Shultz; Bela Denes
Journal:  Can J Urol       Date:  2015-02       Impact factor: 1.344

Review 8.  Low-intensity shockwave therapy for erectile dysfunction: is the evidence strong enough?

Authors:  Mikkel Fode; Georgios Hatzichristodoulou; Ege Can Serefoglu; Paolo Verze; Maarten Albersen
Journal:  Nat Rev Urol       Date:  2017-07-25       Impact factor: 14.432

9.  Extracorporeal shockwave therapy in the treatment of erectile dysfunction: a prospective, randomized, double-blinded, placebo controlled study.

Authors:  Chi-Hang Yee; Eddie Sy Chan; Simon See-Ming Hou; Chi-Fai Ng
Journal:  Int J Urol       Date:  2014-06-17       Impact factor: 3.369

10.  Twelve-Month Efficacy and Safety of Low-Intensity Shockwave Therapy for Erectile Dysfunction in Patients Who Do Not Respond to Phosphodiesterase Type 5 Inhibitors.

Authors:  Amado Bechara; Adolfo Casabé; Walter De Bonis; Pablo Gomez Ciciclia
Journal:  Sex Med       Date:  2016-07-18       Impact factor: 2.491

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Journal:  Biosensors (Basel)       Date:  2022-06-30

2.  Retrospective comparison of focused shockwave therapy and radial wave therapy for men with erectile dysfunction.

Authors:  Shannon S Wu; Kyle J Ericson; Daniel A Shoskes
Journal:  Transl Androl Urol       Date:  2020-10

Review 3.  Restorative Therapies for Erectile Dysfunction: Position Statement From the Sexual Medicine Society of North America (SMSNA).

Authors:  James L Liu; Kevin Y Chu; Andrew T Gabrielson; Run Wang; Landon Trost; Gregory Broderick; Kelvin Davies; Gerald Brock; John Mulhall; Ranjith Ramasamy; Trinity J Bivalacqua
Journal:  Sex Med       Date:  2021-05-14       Impact factor: 2.491

Review 4.  Low-intensity shock wave therapy for the treatment of vasculogenic erectile dysfunction: a narrative review of technical considerations and treatment outcomes.

Authors:  Pedro Simoes de Oliveira; Matthew J Ziegelmann
Journal:  Transl Androl Urol       Date:  2021-06

5.  Evaluation of immediate and short-term efficacy of DualStim therapy with and without intracavernosal umbilical cord-derived Wharton's jelly in patients with erectile dysfunction: Study protocol for a randomized controlled trial.

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