| Literature DB >> 3172205 |
N Vogt1, L Marrot, N Rousseau, B Malfoy, M Leng.
Abstract
We show that chloroacetaldehyde, a chemical compound known to be reactive with unpaired adenine and cytosine residues, reacts with adenine residues (syn conformation) but not with cytosine residues (anti conformation) within Z-DNA. These modified residues are sensitive to cleavage by piperidine, which allows mapping at the single nucleotide level.Entities:
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Year: 1988 PMID: 3172205 DOI: 10.1016/0022-2836(88)90474-3
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469