Literature DB >> 31709450

Clinical Management of Atopic Dermatitis in Adults: Mapping of Expert Opinion in 4 Nordic Countries using a Modified Delphi Process.

Jacob P Thyssen1, Teresa Berents, Maria Bradley, Mette Deleuran, Øystein Grimstad, Laura Korhonen, Tor Langeland, Tore Särnhult, Simon Francis Thomsen, Turid Thune, Carl-Fredrik Wahlgren, Christian Vestergaard, Laura B Kobyletzki, Anita Remitz.   

Abstract

Similarities and differences in the everyday clinical management of moderate-to-severe atopic dermatitis in Nordic countries are unknown. Using a modified Delphi approach, 15 dermatologists from Denmark, Finland, Norway and Sweden completed face-to-face and online questionnaires and participated in summary discussions to map expert opinion on the clinical management of moderate-to-severe atopic dermatitis in these Nordic countries. Through discussions, 6 adult patient profiles, reflecting common disease presentations of atopic dermatitis, were identified. Using these case profiles, diagnostic work-up, treatment goals, patient education and treatment approaches were discussed. Patient education was identified as essential for effective management. A treatment sequence of moderate-to-potent topical glucocorticosteroids and emollients, followed by systemic treatment, was recommended, allowing 3 months to ascertain systemic treatment response before switching, if necessary. Consensus was not reached on systemic treatment choice, reflecting differences in clinical practice and reimbursement between countries. Practical, case-based clinical recommendations were developed for optimal patient care.

Entities:  

Keywords:  Nordic; atopic dermatitis; guidelines; management; treatment; work-up

Mesh:

Year:  2020        PMID: 31709450      PMCID: PMC9128918          DOI: 10.2340/00015555-3369

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   3.875


  25 in total

1.  Effects of cefuroxime axetil on Staphylococcus aureus colonization and superantigen production in atopic dermatitis.

Authors:  M Boguniewicz; H Sampson; S B Leung; R Harbeck; D Y Leung
Journal:  J Allergy Clin Immunol       Date:  2001-10       Impact factor: 10.793

Review 2.  Efficacy and tolerability of proactive treatment with topical corticosteroids and calcineurin inhibitors for atopic eczema: systematic review and meta-analysis of randomized controlled trials.

Authors:  J Schmitt; L von Kobyletzki; A Svensson; C Apfelbacher
Journal:  Br J Dermatol       Date:  2010-11-23       Impact factor: 9.302

3.  Epidemiology of atopic dermatitis in adults: Results from an international survey.

Authors:  S Barbarot; S Auziere; A Gadkari; G Girolomoni; L Puig; E L Simpson; D J Margolis; M de Bruin-Weller; L Eckert
Journal:  Allergy       Date:  2018-02-13       Impact factor: 13.146

4.  Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.

Authors:  Eric L Simpson; Bolanle Akinlade; Marius Ardeleanu
Journal:  N Engl J Med       Date:  2017-03-16       Impact factor: 91.245

5.  The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group.

Authors:  J M Hanifin; M Thurston; M Omoto; R Cherill; S J Tofte; M Graeber
Journal:  Exp Dermatol       Date:  2001-02       Impact factor: 3.960

6.  Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use.

Authors:  A Y Finlay; G K Khan
Journal:  Clin Exp Dermatol       Date:  1994-05       Impact factor: 3.470

Review 7.  Atopic dermatitis endotypes and implications for targeted therapeutics.

Authors:  Tali Czarnowicki; Helen He; James G Krueger; Emma Guttman-Yassky
Journal:  J Allergy Clin Immunol       Date:  2019-01       Impact factor: 10.793

Review 8.  Emollients and moisturisers for eczema.

Authors:  Esther J van Zuuren; Zbys Fedorowicz; Robin Christensen; Adriana Lavrijsen; Bernd WM Arents
Journal:  Cochrane Database Syst Rev       Date:  2017-02-06

9.  Translating Patient-Oriented Eczema Measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor-based methods.

Authors:  C R Charman; A J Venn; J C Ravenscroft; H C Williams
Journal:  Br J Dermatol       Date:  2013-12       Impact factor: 9.302

10.  Characterization of different courses of atopic dermatitis in adolescent and adult patients.

Authors:  D Garmhausen; T Hagemann; T Bieber; I Dimitriou; R Fimmers; T Diepgen; N Novak
Journal:  Allergy       Date:  2013-03-01       Impact factor: 13.146

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  3 in total

1.  Treatment Patterns among Patients with Atopic Dermatitis in Secondary Care: A National, Observational, Non-interventional, Retrospective Study in Sweden.

Authors:  Emma K Johansson; Andreas Brenneche; Dennis Trangbaek; M Natalia Stelmaszuk; Jonatan Freilich; Chris D Anderson
Journal:  Acta Derm Venereol       Date:  2022-09-06       Impact factor: 3.875

2.  Treatment Guidelines for Atopic Dermatitis Since the Approval of Dupilumab: A Systematic Review and Quality Appraisal Using AGREE-II.

Authors:  Stephanie Ghazal; Zainab Ridha; Kathleen D'Aguanno; David Nassim; Andrea Quaiattini; Elena Netchiporouk; Yves Poulin; Sunil Kalia; Danielle Marcoux; Vincent Piguet; Carolyn Jack
Journal:  Front Med (Lausanne)       Date:  2022-03-09

Review 3.  Atopic Dermatitis and Food Allergy: A Complex Interplay What We Know and What We Would Like to Learn.

Authors:  Niki Papapostolou; Paraskevi Xepapadaki; Stamatis Gregoriou; Michael Makris
Journal:  J Clin Med       Date:  2022-07-21       Impact factor: 4.964

  3 in total

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