BACKGROUND: Cancer of the intrahepatic and extrahepatic biliary tracts is characterized by a low incidence and a very heterogeneous appearance. OBJECTIVE: Summary and evaluation of current surgical strategies in the treatment of malignant biliary tract diseases. MATERIAL AND METHODS: An analysis of English language publications as well as European and American guidelines and recommendations for the surgical treatment of malignant diseases of the biliary tract was carried out. The results and recommendations were summarized and evaluated on the basis of experiences in this center. RESULTS: Surgery is considered to be the only curative treatment option; however, prospective randomized studies and existing guidelines are based on limited evidence. Surgical strategies and the extent of resection differ between carcinomas of the intrahepatic and extrahepatic bile ducts depending on localization, size and number of lesions as well as their proximity to surrounding structures. CONCLUSION: Sufficient experience in the treatment of these rare tumors is of special importance for the implementation of individualized overall concepts and for the sufficient performance of the mostly complex resections.
BACKGROUND:Cancer of the intrahepatic and extrahepatic biliary tracts is characterized by a low incidence and a very heterogeneous appearance. OBJECTIVE: Summary and evaluation of current surgical strategies in the treatment of malignant biliary tract diseases. MATERIAL AND METHODS: An analysis of English language publications as well as European and American guidelines and recommendations for the surgical treatment of malignant diseases of the biliary tract was carried out. The results and recommendations were summarized and evaluated on the basis of experiences in this center. RESULTS: Surgery is considered to be the only curative treatment option; however, prospective randomized studies and existing guidelines are based on limited evidence. Surgical strategies and the extent of resection differ between carcinomas of the intrahepatic and extrahepatic bile ducts depending on localization, size and number of lesions as well as their proximity to surrounding structures. CONCLUSION: Sufficient experience in the treatment of these rare tumors is of special importance for the implementation of individualized overall concepts and for the sufficient performance of the mostly complex resections.
Authors: Neal Bhutiani; Charles R Scoggins; Kelly M McMasters; Cecilia G Ethun; George A Poultsides; Timothy M Pawlik; Sharon M Weber; Carl R Schmidt; Ryan C Fields; Kamran Idrees; Ioannis Hatzaras; Perry Shen; Shishir K Maithel; Robert C G Martin Journal: Surgery Date: 2018-01-03 Impact factor: 3.982
Authors: John N Primrose; Richard P Fox; Daniel H Palmer; Hassan Z Malik; Raj Prasad; Darius Mirza; Alan Anthony; Pippa Corrie; Stephen Falk; Meg Finch-Jones; Harpreet Wasan; Paul Ross; Lucy Wall; Jonathan Wadsley; Jeff T R Evans; Deborah Stocken; Raaj Praseedom; Yuk Ting Ma; Brian Davidson; John P Neoptolemos; Tim Iveson; James Raftery; Shihua Zhu; David Cunningham; O James Garden; Clive Stubbs; Juan W Valle; John Bridgewater Journal: Lancet Oncol Date: 2019-03-25 Impact factor: 41.316
Authors: Pim B Olthof; Robert J S Coelen; Jimme K Wiggers; Bas Groot Koerkamp; Massimo Malago; Roberto Hernandez-Alejandro; Stefan A Topp; Marco Vivarelli; Luca A Aldrighetti; Ricardo Robles Campos; Karl J Oldhafer; William R Jarnagin; Thomas M van Gulik Journal: HPB (Oxford) Date: 2017-03-06 Impact factor: 3.647
Authors: Peter Neuhaus; Armin Thelen; Sven Jonas; Gero Puhl; Timm Denecke; Wilfried Veltzke-Schlieker; Daniel Seehofer Journal: Ann Surg Oncol Date: 2011-10-01 Impact factor: 5.344
Authors: Simon Wabitsch; Philipp Konstatnin Haber; Nnange Ekwelle; Anika Kästner; Felix Krenzien; Christian Benzing; Georgi Atanasov; Julia-Sophia Bellingrath; Georg Bauer; Wenzel Schöning; Robert Öllinger; Johann Pratschke; Moritz Schmelzle Journal: J Surg Res Date: 2019-02-26 Impact factor: 2.192
Authors: N Filmann; D Walter; E Schadde; C Bruns; T Keck; H Lang; K Oldhafer; H J Schlitt; M R Schön; E Herrmann; W O Bechstein; A A Schnitzbauer Journal: Br J Surg Date: 2019-07-24 Impact factor: 6.939
Authors: Andreas Andreou; Benjamin Struecker; Nathanael Raschzok; Felix Krenzien; Philipp Haber; Simon Wabitsch; Christoph Waldbaur; Eva-Maria Touet; Anne-Christine Eichelberg; Georgi Atanasov; Matthias Biebl; Marcus Bahra; Robert Öllinger; Moritz Schmelzle; Johann Pratschke Journal: Surg Oncol Date: 2018-10-09 Impact factor: 3.279
Authors: Sandra Pavicevic; Sophie Reichelt; Deniz Uluk; Isabella Lurje; Cornelius Engelmann; Dominik P Modest; Uwe Pelzer; Felix Krenzien; Nathanael Raschzok; Christian Benzing; Igor M Sauer; Sebastian Stintzing; Frank Tacke; Wenzel Schöning; Moritz Schmelzle; Johann Pratschke; Georg Lurje Journal: Cancers (Basel) Date: 2022-02-17 Impact factor: 6.639