| Literature DB >> 31700930 |
Jiao Chen1,2, Liangfei Ao1,2, Jing Yang1,2.
Abstract
Long non-coding RNAs (lncRNAs) have been key regulators of gene expression in innate and adaptive immunity. Although lncRNAs have been reported to be associated with some diseases, its expression and function in diseases related to inflammation and immunity are still unknown. We reviewed how lncRNA regulated transcription and controlled the function and balance of the cells in the immune response. In addition, we discussed the impacts and challenges of lncRNAs on immunity in diseases. 2019 Annals of Translational Medicine. All rights reserved.Entities:
Keywords: Immunomodulating; epigenetics; gene expression; long non-coding RNA (lncRNA)
Year: 2019 PMID: 31700930 PMCID: PMC6803193 DOI: 10.21037/atm.2019.08.37
Source DB: PubMed Journal: Ann Transl Med ISSN: 2305-5839