| Literature DB >> 31700195 |
Shaobao Liu1, Ru Tao2, Ming Wang2, Jin Tian3, Guy M Genin4, Tian Jian Lu1, Feng Xu2.
Abstract
Hydrostatic pressure (HP) regulates diverse cell behaviors including differentiation, migration, apoptosis, and proliferation. Abnormal HP is associated with pathologies including glaucoma and hypertensive fibrotic remodeling. In this review, recent advances in quantifying and predicting how cells respond to HP across several tissue systems are presented, including tissues of the brain, eye, vasculature and bladder, as well as articular cartilage. Finally, some promising directions on the study of cell behaviors regulated by HP are proposed.Entities:
Keywords: cell micro-environment; cell volume; mechanobiology; mechanotransduction
Year: 2019 PMID: 31700195 PMCID: PMC6808007 DOI: 10.1115/1.4043947
Source DB: PubMed Journal: Appl Mech Rev ISSN: 0003-6900 Impact factor: 7.281