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Literature DB >> 3169590

Reduced number of hemidesmosomes in the corneal epithelium of diabetics with proliferative vitreoretinopathy.

C A Tabatabay¹, M Bumbacher, B Baumgartner, P M Leuenberger.

Abstract

Morphometry on transmission electron micrographs of the hemidesmosomal width was related to the length of the basal plasmalemma in corneal epithelium biopsy specimens. The basal plasmalemma length occupied by hemidesmosomes showed a mean fraction of 0.227 in eight patients undergoing cataract extraction or vitrectomy for diabetic proliferative vitreoretinopathy. In seven non-diabetic control patients of comparable age and sex undergoing cataract or pterygium surgery, 0.412 of the basal plasmalemma was covered by hemidesmosomes. A reduction in hemidesmosomes (P less than 0.001) may contribute to a weakness in the adhesion of diabetic corneal epithelium to the underlying stroma.

Entities: Disease Species

Mesh：

Year: 1988 PMID： 3169590 DOI： 10.1007/bf02172973

Source DB: PubMed Journal: Graefes Arch Clin Exp Ophthalmol ISSN： 0721-832X Impact factor: 3.117

10 in total

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Authors: Whitney L Stuard; Rossella Titone; Danielle M Robertson
Journal: Eye Contact Lens Date: 2020-09 Impact factor: 2.018