| Literature DB >> 31695345 |
Steven Phu1,2, Sara Vogrin1,2, Ahmed Al Saedi1,2, Gustavo Duque1,2.
Abstract
PURPOSE: Exercise programs designed for falls prevention have been proven effective in reducing falls by approximately 21%. Virtual reality may provide a viable alternative intervention for falls prevention. This study compared the effects of virtual reality training using the Balance Rehabilitation Unit (BRU) versus exercise using a modified Otago Exercise Programme (EX) on improving balance and physical performance in the short-term restorative care setting of the Gait and Balance Gym (Gabagym). PATIENTS AND METHODS: This was a pre- and post-intervention study of 195 participants (median age 78 years, IQR 73-84; 67% female) who presented with a risk and/or history of falls. Participants were assigned to either EX (n=82) or BRU (n=63). Supervised sessions occurred twice a week for 6 weeks. Participants receiving interventions were compared to a separate group (n=50) with similar characteristics who did not receive any intervention. Balance and physical performance were assessed at initial and final attendance and included the 5 Times Sit to Stand (5STS) test, Timed Up and Go (TUG), gait speed and posturography assessment using the BRU. Fear of falling was assessed using the Falls Efficacy Scale. Handgrip strength and adherence were also monitored.Entities:
Keywords: exercise; falls; fractures; posture; virtual reality
Mesh:
Year: 2019 PMID: 31695345 PMCID: PMC6717859 DOI: 10.2147/CIA.S220890
Source DB: PubMed Journal: Clin Interv Aging ISSN: 1176-9092 Impact factor: 4.458
Baseline characteristics of included participants reported as median (IQR)
| Baseline characteristics | BRU, N=63 | Exercise, N=82 | Control, N=50 | Between-group |
|---|---|---|---|---|
| Age, y | 79 (74, 84) | 76 (71, 82) | 79 (72, 82) | 0.37 |
| Sex | 0.55 | |||
| Male, n (%) | 19 (30.2) | 31 (37.8) | 15 (30%) | |
| Female, n (%) | 44 (69.8) | 51 (62.2) | 35 (70%) | |
| Body mass index, kg/m2 | 27.0 (25.0, 31.0) | 27.0 (23.5, 31.0) | 28.5 (24.1, 32.6) | 0.60 |
| Handgrip strength (kg) | 19 (16, 25) | 20.5 (17, 27) | 22 (16, 28) | 0.42 |
| 5 Sit to Stand, s | 21.1 (16.9, 28.8) | 18.5 (15.4, 26.4) | 17.8 (14.8, 22.9) | 0.11 |
| Timed Up and Go, s | 15.0 (11.8, 19.4) | 11.9 (10.0, 15.8) | 16.0 (10.2, 21.8) | 0.005 |
| Gait Speed, m/s | 0.78 (0.58, 0.91) | 1.03 (0.80, 1.13) | 0.80 (0.52, 0.98) | 0.002 |
| Limits of Stability, cm2 | 111 (80, 144) | 132 (91, 156) | 126 (53, 161) | 0.55 |
| Falls Efficacy Scale – International (16–64) | 34 (27, 39) | 33 (25, 41) | 32 (24, 43) | 0.93 |
Abbreviation: BRU, balance rehabilitation unit.
Pre- and post-program results in physical performance and subjective measures for EX, Balance Rehabilitation Unit (BRU) and non-intervention groups
| Assessment | Intervention | Pre | Post | Change | |||||
|---|---|---|---|---|---|---|---|---|---|
| N | Median (IQR) | N | Median (IQR) | Unit | Mean (95% CI) | ||||
| Hand grip strength, kg | Exercise | 82 | 20.50 (17.00, 27.00) | 59 | 24.00 (20.50, 28.50) | % | 11.32 (5.84, 17.08) | <0.001 | 0.021 |
| BRU | 63 | 19.00 (16.00, 25.00) | 44 | 21.50 (18.25, 26.00) | % | 6.82 (0.77, 13.24) | 0.027 | ||
| Control | 49 | 22.00 (16.00, 28.00) | 48 | 20.50 (18.00, 25.50) | % | −0.07 (−5.61, 5.79) | 0.98 | ||
| 5 times Sit to Stand, s | Exercise | 79 | 18.52 (15.40, 26.40) | 59 | 13.90 (11.50, 16.80) | % | −29.84 (−35.23, −23.99) | <0.001 | 0.296 |
| BRU | 61 | 21.10 (16.90, 28.80) | 43 | 16.40 (11.90, 19.90) | % | −26.69 (−33.22, −19.52) | <0.001 | ||
| Control | 37 | 17.76 (14.83, 22.90) | 30 | 15.29 (11.25, 17.71) | % | −21.79 (−30.00, −12.62) | <0.001 | ||
| Timed Up and Go, s | Exercise | 78 | 11.90 (10.30, 15.80) | 56 | 10.05 (8.80, 12.30) | % | −20.33 (−24.99, −15.38) | <0.001 | <0.001 |
| BRU | 60 | 15.00 (11.85, 19.40) | 42 | 11.30 (9.30, 14.90) | % | −23.30 (−28.42, −17.83) | <0.001 | ||
| Control | 47 | 15.96 (10.21, 21.75) | 43 | 14.14 (10.86, 19.90) | % | −4.31 (−10.68, 2.50) | 0.209 | ||
| Four Square Step Test, s | Exercise | 42 | 15.50 (13.10, 18.80) | 37 | 12.30 (10.40, 14.10) | % | −23.95 (−30.45, −16.83) | <0.001 | 0.378 |
| BRU | 31 | 19.50 (14.10, 22.70) | 25 | 14.60 (11.90, 17.70) | % | −18.87 (−26.89, −9.96) | <0.001 | ||
| Control | 30 | 14.62 (11.19, 18.38) | 25 | 13.83 (11.71, 18.70) | % | −16.72 (−24.45, −8.20) | <0.001 | ||
| Gait speed, m/s | Exercise | 47 | 1.03 (0.80, 1.13) | 30 | 1.13 (1.00, 1.25) | m/s | 0.15 (0.10, 0.20) | <0.001 | 0.021 |
| BRU | 48 | 0.78 (0.58, 0.91) | 34 | 0.94 (0.79, 1.15) | m/s | 0.12 (0.07, 0.17) | <0.001 | ||
| Control | 48 | 0.80 (0.52, 0.98) | 44 | 0.78 (0.59, 1.03) | m/s | 0.06 (0.02, 0.10) | 0.007 | ||
| Falls Efficacy Scale – International | Exercise | 73 | 32 (25, 41) | 51 | 26 (22, 33) | % | −15.7 (−21.6, −9.5) | <0.001 | 0.013 |
| BRU | 61 | 34 (27, 39) | 40 | 27 (24, 35) | % | −11.3 (−18.2, −3.8) | 0.004 | ||
| Control | 48 | 32 (24, 43) | 49 | 34 (23, 43) | % | −1.6 (−8.8, 6.1) | 0.676 | ||
Abbreviation: BRU, Balance Rehabilitation Unit.
Figure 1Percentage change for handgrip strength, five time sit to stand (5 STS), timed up and go (TUG), four square step test (FSST) and falls efficacy scale (FES-I) assessments. Absolute change included for gait speed. p-values for comparisons between pre and post intervention are listed on the right hand side for each intervention. Significant difference was found between the exercise and BRU groups compared to control (non-intervention) for handgrip strength, TUG, gait speed and fear of falling (FES-I) assessments.
Pre- and post-program results for the posturography assessment in the exercise and Balance Rehabilitation Unit (BRU) and non-intervention groups
| Assessment | Intervention | Pre | Post | Change | |||||
|---|---|---|---|---|---|---|---|---|---|
| N | Median (IQR) | N | Median (IQR) | Unit | Mean (95% CI) | ||||
| Limits of stability, cm2 | Exercise | 33 | 132 (91, 156) | 21 | 150 (128, 182) | % | 23.76 (5.19, 45.60) | 0.01 | 0.008 |
| BRU | 62 | 111 (80, 144) | 42 | 158 (131, 187) | % | 36.93 (22.03, 53.65) | <0.001 | ||
| Control | 45 | 126 (53, 161) | 42 | 120 (43, 169) | % | 5.08 (−6.83, 18.51) | 0.419 | ||
| Eyes Open Ellipse Area, cm2 | Exercise | 33 | 5.83 (3.12, 12.38) | 21 | 6.86 (3.18, 12.84) | % | 4.03 (−24.52, 43.39) | 0.809 | 0.456 |
| BRU | 62 | 6.81 (4.13, 12.60) | 42 | 6.33 (3.53, 10.45) | % | −18.96 (−35.49, 1.81) | 0.071 | ||
| Control | 45 | 4.28 (2.70, 9.26) | 42 | 4.21 (2.68, 5.86) | % | −13.97 (−32.33, 9.38) | 0.219 | ||
| Eyes Closed Ellipse Area, cm2 | Exercise | 33 | 6.08 (3.92, 15.24) | 21 | 5.93 (4.45, 14.10) | % | −9.73 (−33.94, 23.35) | 0.52 | 0.140 |
| BRU | 62 | 9.91 (5.63, 16.98) | 42 | 6.55 (4.08, 11.67) | % | −29.97 (−43.90, −12.59) | 0.002 | ||
| Control | 40 | 5.36 (2.46, 10.41) | 38 | 4.63 (2.83, 9.64) | % | −3.52 (−24.85, 23.85) | 0.778 | ||
| Foam Eyes Closed Ellipse Area, cm2 | Exercise | 23 | 20.42 (15.09, 30.11) | 12 | 16.45 (14.05, 20.63) | % | −23.26 (−40.68, −0.72) | 0.044 | 0.310 |
| BRU | 44 | 28.81 (17.54, 39.80) | 29 | 20.44 (15.11, 28.83) | % | −21.01 (−33.22, −6.56) | 0.006 | ||
| Control | 23 | 18.58 (11.98, 37.11) | 24 | 18.64 (11.68, 33.89) | % | −4.61 (−22.84, 17.93) | 0.663 | ||
| Saccadic Ellipse Area, cm2 | Exercise | 27 | 6.32 (2.81, 10.58) | 17 | 6.75 (3.72, 14.11) | % | −0.77 (−24.45, 30.32) | 0.956 | 0.455 |
| BRU | 60 | 7.05 (4.20, 11.89) | 40 | 6.63 (3.91, 10.64) | % | −10.85 (−25.39, 6.54) | 0.207 | ||
| Control | 39 | 4.59 (2.09, 9.40) | 36 | 4.87 (2.59, 8.53) | % | 5.65 (−13.64, 29.24) | 0.593 | ||
| Visuo-Vestibular Interaction Ellipse Area, cm2 | Exercise | 24 | 9.51 (5.99, 13.85) | 15 | 10.69 (7.53, 19.46) | % | −13.34 (−29.98, 7.26) | 0.188 | 0.928 |
| BRU | 56 | 13.41 (7.88, 24.18) | 39 | 12.98 (7.87, 18.68) | % | −12.33 (−23.15, 0.02) | 0.05 | ||
| Control | n/a | n/a | n/a | ||||||
Abbreviation: BRU, Balance Rehabilitation Unit.
Figure 2Percentage change for the posturography assessment results for limits of stability (LOS) and ellipse areas for the following tasks: eyes open (EOEA), eyes closed task (ECEA), foam eyes closed (FECEA), saccadic (SEA), visuo-vestibular interaction (VVIEA). p-values for comparisons between pre and post intervention are listed on the right hand side for each intervention. Although the BRU group reported larger and more significant changes, only improvements in limits of stability were significantly different between groups.
Abbreviation: BRU, Balance Rehabilitation Unit.