Ahmet Namazov1, Ofer Gemer2, Limor Helpman3, Nasreen Hag-Yahia3, Ram Eitan4, Oded Raban4, Zvi Vaknin5, Sophia Leytes6, Ofer Lavie7, Amnon Amit8, Tally Levy6, Michael Volodarsky2, Inbar Ben Shachar9, Ilan Atlas10, Ilan Bruchim11, Alon Ben-Arie12. 1. Department of Obstetrics and Gynecology, Barzilai University Medical Center, Faculty of Health Sciences, Ben-Gurion University of Negev, Beer-Sheva, Ashkelon, Israel. Electronic address: enamazov@gmail.com. 2. Department of Obstetrics and Gynecology, Barzilai University Medical Center, Faculty of Health Sciences, Ben-Gurion University of Negev, Beer-Sheva, Ashkelon, Israel. 3. Department of Obstetrics and Gynecology, Meir Medical Center, Sackler School of Medicine, Tel Aviv University, Kfar Saba, Israel. 4. Department of Obstetrics and Gynecology, Rabin Medical Center, Sackler School of Medicine, Tel Aviv University, Petah Tikva, Israel. 5. Department of Obstetrics and Gynecology, Assaf Haroffe Medical Center, Sackler School of Medicine, Tel Aviv University, Zrifin, Israel. 6. Department of Obstetrics and Gynecology, Wolfson Medical Center, Sackler School of Medicine, Tel Aviv University, Holon, Israel. 7. Department of Obstetrics and Gynecology, Carmel Medical Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel. 8. Department of Obstetrics and Gynecology, Rambam Medical Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel. 9. Department of Obstetrics and Gynecology, Ziv Medical Center, Bar Ilan University, Zefat, Israel. 10. Department of Obstetrics and Gynecology, Poriya Medical Center, Bar Ilan University, Tiberia, Israel. 11. Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Rappaport Faculty of Medicine, Technion, Hedera, Israel. 12. Department of Obstetrics and Gynecology, Kaplan Medical Center, Hebrew University, Rehovot, Israel.
Abstract
OBJECTIVE: To compare survival measures of women with early-stage endometrial cancer who underwent either hysteroscopy or a non-hysteroscopic procedure as a diagnostic procedure. STUDY DESIGN: An Israel Gynecologic Oncology Group multicenter study of 1324 patients with stage I endometrial cancer who underwent surgery between 2002 and 2014. Patients were divided into two groups: hysteroscopy and non-hysteroscopy (curettage or office endometrial biopsy). Clinical, pathological, and survival measures were compared between the groups. RESULTS: There were 355 patients in the hysteroscopy group and 969 patients in the non-hysteroscopy group. The median follow-up was 52 months (range 12-120 months). There were no differences between the groups in the 5-year recurrence-free survival (90.2% vs. 88.2%; p = 0.53), disease-specific survival (93.4% vs. 91.7%; p = 0.5), and overall survival (86.2% vs. 80.6%; p = 0.22). CONCLUSION: Our findings affirm that hysteroscopy does not compromise the survival of patients with early-stage endometrial cancer.
OBJECTIVE: To compare survival measures of women with early-stage endometrial cancer who underwent either hysteroscopy or a non-hysteroscopic procedure as a diagnostic procedure. STUDY DESIGN: An Israel Gynecologic Oncology Group multicenter study of 1324 patients with stage I endometrial cancer who underwent surgery between 2002 and 2014. Patients were divided into two groups: hysteroscopy and non-hysteroscopy (curettage or office endometrial biopsy). Clinical, pathological, and survival measures were compared between the groups. RESULTS: There were 355 patients in the hysteroscopy group and 969 patients in the non-hysteroscopy group. The median follow-up was 52 months (range 12-120 months). There were no differences between the groups in the 5-year recurrence-free survival (90.2% vs. 88.2%; p = 0.53), disease-specific survival (93.4% vs. 91.7%; p = 0.5), and overall survival (86.2% vs. 80.6%; p = 0.22). CONCLUSION: Our findings affirm that hysteroscopy does not compromise the survival of patients with early-stage endometrial cancer.