| Literature DB >> 31689520 |
Shuang Hu1, Su-Wen Li2, Qi Yan3, Xiang-Peng Hu4, Liang-Yun Li1, Hong Zhou1, Lin-Xin Pan3, Jun Li1, Chuan-Pu Shen5, Tao Xu6.
Abstract
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide that afflicts human health. With the in-depth study of the disease, its pathogenesis has gradually become clear. Although great breakthroughs have been made in the research of ALD, the research and development of drugs related to ALD has lagged behind seriously. However, natural products have always inspired the development of drugs. Meanwhile, there is evidence that some natural products can also play a certain role in the treatment of ALD. Thus, we reviewed the natural products, extracts and formulations with potential anti-ALD activities by consulting the relevant data in the databases of PubMed, Web of Science and CNKI databases, in order to elucidate the regulated mechanism of these natural products. Sum up, the insights provided in present review will be needed for further exploration of botanical drugs in the development of ALD therapy.Entities:
Keywords: ALD; Extracts; Formulations; Natural products
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Year: 2019 PMID: 31689520 DOI: 10.1016/j.phrs.2019.104501
Source DB: PubMed Journal: Pharmacol Res ISSN: 1043-6618 Impact factor: 7.658