Literature DB >> 31689520

Natural products, extracts and formulations comprehensive therapy for the improvement of motor function in alcoholic liver disease.

Shuang Hu1, Su-Wen Li2, Qi Yan3, Xiang-Peng Hu4, Liang-Yun Li1, Hong Zhou1, Lin-Xin Pan3, Jun Li1, Chuan-Pu Shen5, Tao Xu6.   

Abstract

Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide that afflicts human health. With the in-depth study of the disease, its pathogenesis has gradually become clear. Although great breakthroughs have been made in the research of ALD, the research and development of drugs related to ALD has lagged behind seriously. However, natural products have always inspired the development of drugs. Meanwhile, there is evidence that some natural products can also play a certain role in the treatment of ALD. Thus, we reviewed the natural products, extracts and formulations with potential anti-ALD activities by consulting the relevant data in the databases of PubMed, Web of Science and CNKI databases, in order to elucidate the regulated mechanism of these natural products. Sum up, the insights provided in present review will be needed for further exploration of botanical drugs in the development of ALD therapy.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  ALD; Extracts; Formulations; Natural products

Mesh:

Substances:

Year:  2019        PMID: 31689520     DOI: 10.1016/j.phrs.2019.104501

Source DB:  PubMed          Journal:  Pharmacol Res        ISSN: 1043-6618            Impact factor:   7.658


  3 in total

1.  Deletion of p38γ attenuates ethanol consumption- and acetaminophen-induced liver injury in mice through promoting Dlg1.

Authors:  Shuang Hu; Yan Yao; Ze-Yuan Wei; Shu-Xian Wang; Yin-Cui Wu; Ying Hu; Chen-Chen Yang; Jing-Li Min; Liang-Yun Li; Hong Zhou; Jun-Fa Yang; Jun Li; Tao Xu
Journal:  Acta Pharmacol Sin       Date:  2021-11-17       Impact factor: 7.169

2.  A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway.

Authors:  Dongjian Han; Fuhang Wang; Bo Wang; Zhentao Qiao; Xinyue Cui; Yi Zhang; Qingjiao Jiang; Miaomiao Liu; Jiahong Shangguan; Xiaohui Zheng; Yajun Bai; Chunyan Du; Deliang Shen
Journal:  Front Pharmacol       Date:  2022-02-03       Impact factor: 5.810

3.  TMEM88 Modulates Lipid Synthesis and Metabolism Cytokine by Regulating Wnt/β-Catenin Signaling Pathway in Non-Alcoholic Fatty Liver Disease.

Authors:  Huan Zhou; Xingyu Zhu; Yan Yao; Yue Su; Jing Xie; Minhui Zhu; Cuixia He; Jiaxiang Ding; Yuanyuan Xu; Rongfang Shan; Ying Wang; Xiangdi Zhao; Yuzhou Ding; Bingyan Liu; Zhonghuan Shao; Yuanyuan Liu; Tao Xu; Yunqiu Xie
Journal:  Front Pharmacol       Date:  2022-01-04       Impact factor: 5.810

  3 in total

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