| Literature DB >> 31685459 |
Hervé Volland1, Delphine Girlich2,3, Marine Laguide2,3, Camille Gonzalez2,3, Virginie Paris2,3, Maxime Laroche4, Saoussen Oueslati2,3, Laurent Dortet2,3,5,6, Stéphanie Simon1, Thierry Naas7,3,5,6.
Abstract
Here, we evaluated the immunochromatographic assay NG-Test Carba 5v2 (NG-Biotech), with improved IMP variant detection on 31 IMP producers, representing the different branches of the IMP phylogeny, including 32 OXA-48, 19 KPC, 12 VIM, 14 NDM, and 13 multiple carbapenemase producers (CPs), 13 CPs that were not targeted, and 13 carbapenemase-negative isolates. All tested IMP variants were accurately detected without impairing detection of the other carbapenemases. Thus, NG-Test Carba 5v2 is now well adapted to countries with high IMP prevalence and to the epidemiology of CP-Pseudomonas aeruginosa, where IMPs are most frequently detected.Entities:
Keywords: CPEs; Enterobacteraleszzm321990; IMP; KPC; LFIA; NDM; OXA-48; Pseudomonas aeruginosazzm321990; VIM; detection; rapid diagnostic
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Year: 2019 PMID: 31685459 PMCID: PMC7187612 DOI: 10.1128/AAC.01940-19
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191