| Literature DB >> 31683612 |
Kateřina Škrlová1,2, Kateřina Malachová3, Alexandra Muñoz-Bonilla4, Dagmar Měřinská5, Zuzana Rybková6, Marta Fernández-García7, Daniela Plachá8,9.
Abstract
Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient's body, which presents a number of complications and can also endanger the patient's life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents.Entities:
Keywords: antimicrobial agents; antimicrobial effects; biodegradable polymer; medicine; polylactide; stent
Year: 2019 PMID: 31683612 PMCID: PMC6915381 DOI: 10.3390/nano9111548
Source DB: PubMed Journal: Nanomaterials (Basel) ISSN: 2079-4991 Impact factor: 5.076