Literature DB >> 31680546

Correlation between Argus II array-retina distance and electrical thresholds of stimulation is improved by measuring the entire array.

Lucy T Xu1, Aleksandra V Rachitskaya1, Meghan J DeBenedictis1, James Bena2, Shannon Morrison2, Alex Yuan1.   

Abstract

PURPOSE: To describe two methods of measuring Argus II array-retina distance and to correlate array-retina distance to electrode stimulation thresholds.
METHODS: This was a case series of eight patients implanted with the Argus II. Spectral domain-optical coherence tomography array-retina distance was measured by two methods and correlated to corresponding electrode thresholds: (1) array-retina distance at each array corner and the largest array-retina distance and (2) using manual optical coherence tomography segmentation, the average array-retina distance was determined for each group of four electrodes. Patients 1-5 and 6-8 were analyzed separately due to a different threshold programming software.
RESULTS: The Spearman's rank coefficient between array-retina distance and thresholds was -0.006 (p = 0.98) for patients 1-5, and 0.16 (p = 0.59) for patients 6-8 with the first method. The Spearman's rank coefficient was 0.25 (p < 0.001) for patients 1-5 and 0.36 (p < 0.001) for patients 6-8 with the second method.
CONCLUSION: There is a positive correlation between array-retina distance and threshold measurements when measuring the entire array but not when using a faster measurement method of four corners and largest array-retina distance.

Entities:  

Keywords:  Argus; array–retina distance; optical coherence tomography; retinitis pigmentosa

Mesh:

Year:  2019        PMID: 31680546     DOI: 10.1177/1120672119885799

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  4 in total

1.  A Patient-Specific Computational Framework for the Argus II Implant.

Authors:  Kathleen E Finn; Hans J Zander; Robert D Graham; Scott F Lempka; James D Weiland
Journal:  IEEE Open J Eng Med Biol       Date:  2020-06-11

2.  Interobserver Agreement of Electrode to Retina Distance Measurements in a Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis.

Authors:  Carla J Abbott; Elizabeth K Baglin; Maria Kolic; Myra B McGuinness; Samuel A Titchener; Kiera A Young; Jonathan Yeoh; Chi D Luu; Lauren N Ayton; Matthew A Petoe; Penelope J Allen
Journal:  Transl Vis Sci Technol       Date:  2022-09-01       Impact factor: 3.048

3.  Factors affecting two-point discrimination in Argus II patients.

Authors:  Ezgi I Yücel; Roksana Sadeghi; Arathy Kartha; Sandra Rocio Montezuma; Gislin Dagnelie; Ariel Rokem; Geoffrey M Boynton; Ione Fine; Michael Beyeler
Journal:  Front Neurosci       Date:  2022-08-24       Impact factor: 5.152

4.  A Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis: Long-Term Observation of the Electrode-Tissue Interface.

Authors:  Samuel A Titchener; David A X Nayagam; Jessica Kvansakul; Maria Kolic; Elizabeth K Baglin; Carla J Abbott; Myra B McGuinness; Lauren N Ayton; Chi D Luu; Steven Greenstein; William G Kentler; Mohit N Shivdasani; Penelope J Allen; Matthew A Petoe
Journal:  Transl Vis Sci Technol       Date:  2022-06-01       Impact factor: 3.048

  4 in total

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