Literature DB >> 316752

Decrease of IgA-specific suppressor T cell activity in patients with IgA nephropathy.

H Sakai, Y Nomoto, S Arimori.   

Abstract

The activity of IgA-specific suppressor T cells was lower in eight patients with IgA nephropathy than in six patients with chronic proliferative glomerulonephritis without glomerular deposition of IgA, two patients with acute glomerulonephritis, or five healthy adult controls. It was determined by the quantitation of immunoglobulins produced from pokeweed mitogen-stimulated B cells cultured with the T cell supernatant (TCS) obtained from concanavalin A-stimulated T cells. Results from a study on an identical twin sister with IgA nephropathy suggested that the decreased activity of IgA-specific suppressor T cells might not be a cause but a result of increased IgA-bearing lymphocytes and serum IgA in patients with IgA nephropathy.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 316752      PMCID： PMC1537852     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  11 in total

1.  Suppression of immunoglobulin synthesis and secretion by peripheral blood lymphocytes from normal donors.

Authors:  S A Schwartz; L Shou; R A Good; Y S Choi
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

2.  Increase of IgA-bearing lymphocytes in peripheral blood from patients with IgA nephropathy.

Authors:  Y Nomoto; H Sakai; S Arimori
Journal:  Am J Clin Pathol       Date:  1979-02       Impact factor: 2.493

3.  Functional assessment of a B cell defect in patients with selective IgA deficiency.

Authors:  J T Cassidy; G Oldham; T A Platts-Mills
Journal:  Clin Exp Immunol       Date:  1979-02       Impact factor: 4.330

Review 4.  IgA-Associated glomerulonepbritis.

Authors:  D C Lowance; J D Mullins; J J McPhaul
Journal:  Int Rev Exp Pathol       Date:  1977

5.  Activation of human B lymphocytes. III. Concanavalin A-induced generation of suppressor cells of the plaque-forming cell response of normal human B lymphocytes.

Authors:  B F Haynes; A S Fauci
Journal:  J Immunol       Date:  1977-06       Impact factor: 5.422

6.  Biological expressions of lymphocyte activation. 3. Suppression of plaque-forming cell responses in vitro by supernatant fluids from concanavalin A-activated spleen cell cultures.

Authors:  R R Rich; C W Pierce
Journal:  J Immunol       Date:  1974-04       Impact factor: 5.422

7.  Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.

Authors:  T A Waldmann; M Durm; S Broder; M Blackman; R M Blaese; W Strober
Journal:  Lancet       Date:  1974-09-14       Impact factor: 79.321

8.  IgA glomerular deposits in renal disease.

Authors:  J Berger
Journal:  Transplant Proc       Date:  1969-12       Impact factor: 1.066

9.  "Sandwich" solid phase radioimmunoassay for the quantitative deterimination of human immunoglobulins.

Authors:  S E Salmon; G Mackey; H H Fudenberg
Journal:  J Immunol       Date:  1969-07       Impact factor: 5.422

10.  Lymphocyte recovery, purification, and stimulation. A prospective study.

Authors:  K L Parker; D M Schreinemachers; H J Meuwissen
Journal:  Transplantation       Date:  1972-07       Impact factor: 4.939
View more
  34 in total

1.  T and B cell responses following immunization with tetanus toxoid in IgA nephropathy.

Authors:  F Fortune; M Courteau; D G Williams; T Lehner
Journal:  Clin Exp Immunol       Date:  1992-04       Impact factor: 4.330

2.  Immune response of tonsillar lymphocytes to Haemophilus parainfluenzae in patients with IgA nephropathy.

Authors:  S Suzuki; S Fujieda; H Sunaga; H Sugimoto; C Yamamoto; H Kimura; T Abo; F Gejyo
Journal:  Clin Exp Immunol       Date:  2000-02       Impact factor: 4.330

3.  Increase of IgA-specific switch T cells in patients with IgA nephropathy.

Authors:  H Sakai; M Miyazaki; M Endoh; Y Nomoto
Journal:  Clin Exp Immunol       Date:  1989-12       Impact factor: 4.330

4.  T-cell epitopes recognized within the 65,000 MW hsp in patients with IgA nephropathy.

Authors:  K Warr; F Fortune; S Namie; A Wilson; T Shinnick; R Van der Zee; G Williams; T Lehner
Journal:  Immunology       Date:  1997-07       Impact factor: 7.397

5.  IgA polyspecific autoantibodies in IgA nephropathy.

Authors:  P Matsiota; P Dosquet; H Louzir; E Druet; P Druet; S Avrameas
Journal:  Clin Exp Immunol       Date:  1990-03       Impact factor: 4.330

6.  Charge distribution of plasma IgA in IgA nephropathy.

Authors:  T Harada; P Hobby; M Courteau; J F Knight; D G Williams
Journal:  Clin Exp Immunol       Date:  1989-08       Impact factor: 4.330

Review 7.  IgA nephropathy.

Authors:  M C Béné; G Faure
Journal:  Springer Semin Immunopathol       Date:  1987

8.  Serum IgG subclasses and IgM imbalances in adult IgA mesangial glomerulonephritis and idiopathic Henoch-Schoenlein purpura.

Authors:  G Rostoker; M A Pech; S Del Prato; M Petit-Phar; A Ben Maadi; J M Dubert; P Lang; B Weil; G Lagrue
Journal:  Clin Exp Immunol       Date:  1989-01       Impact factor: 4.330

9.  IgA1 and IgA2 immune complexes in primary IgA nephropathy and Henoch-Schönlein nephritis.

Authors:  R Coppo; B Basolo; G Piccoli; G Mazzucco; M R Bulzomì; D Roccatello; M De Marchi; A O Carbonara; G Barbiano di Belgiojoso
Journal:  Clin Exp Immunol       Date:  1984-09       Impact factor: 4.330

10.  Deposition of polymeric IgA1 in idiopathic mesangial IgA-glomerulonephritis.

Authors:  R Waldherr; H P Seelig; M Rambausek; K Andrassy; E Ritz
Journal:  Klin Wochenschr       Date:  1983-09-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.