SIGNIFICANCE: Obstructive sleep apnea has been linked to the development and progression of diabetic retinopathy. In this study, diabetic patients compliant with continuous positive airway pressure therapy (CPAP) for sleep apnea were less likely to have retinopathy, emphasizing the benefits and potential therapeutic role of CPAP in individuals with both conditions. PURPOSE: The aim of this study was to compare the prevalence of diabetic retinopathy in type 2 diabetic patients with obstructive sleep apnea who were compliant with CPAP therapy with those who were not compliant with CPAP therapy. METHODS: A retrospective cross-sectional review of type 2 diabetic patients using CPAP for obstructive sleep apnea was conducted. The prevalence of retinopathy was identified, and groups with and without retinopathy were compared using univariate analyses and multivariate logistic regression. RESULTS: The prevalence of retinopathy was 19.6% (n = 321). Retinopathy was significantly less prevalent in those compliant with CPAP (odds ratio, 0.54; 95% confidence interval, 0.31 to 0.94; P = .04). The relationship remained statistically significant when adjusting for other factors known to impact the course of diabetic eye disease. CONCLUSIONS: Increased CPAP compliance may mitigate the risk of developing diabetic retinopathy in type 2 diabetic patients with obstructive sleep apnea.
SIGNIFICANCE: Obstructive sleep apnea has been linked to the development and progression of diabetic retinopathy. In this study, diabeticpatients compliant with continuous positive airway pressure therapy (CPAP) for sleep apnea were less likely to have retinopathy, emphasizing the benefits and potential therapeutic role of CPAP in individuals with both conditions. PURPOSE: The aim of this study was to compare the prevalence of diabetic retinopathy in type 2 diabeticpatients with obstructive sleep apnea who were compliant with CPAP therapy with those who were not compliant with CPAP therapy. METHODS: A retrospective cross-sectional review of type 2 diabeticpatients using CPAP for obstructive sleep apnea was conducted. The prevalence of retinopathy was identified, and groups with and without retinopathy were compared using univariate analyses and multivariate logistic regression. RESULTS: The prevalence of retinopathy was 19.6% (n = 321). Retinopathy was significantly less prevalent in those compliant with CPAP (odds ratio, 0.54; 95% confidence interval, 0.31 to 0.94; P = .04). The relationship remained statistically significant when adjusting for other factors known to impact the course of diabetic eye disease. CONCLUSIONS: Increased CPAP compliance may mitigate the risk of developing diabetic retinopathy in type 2 diabeticpatients with obstructive sleep apnea.
Authors: Babak Mokhlesi; Daniela Grimaldi; Guglielmo Beccuti; Varghese Abraham; Harry Whitmore; Fanny Delebecque; Eve Van Cauter Journal: Am J Respir Crit Care Med Date: 2016-08-15 Impact factor: 21.405
Authors: Jamie Chung Mei Lam; Agnes Yuen Kwan Lai; Terence Chi Chun Tam; Michele Mae Ann Yuen; Karen Siu Ling Lam; Mary Sau Man Ip Journal: Sleep Breath Date: 2016-11-05 Impact factor: 2.816
Authors: Urmi Sheth; Rebecca S Monson; Bharati Prasad; Ashima S Sahni; Sara Matani; Tomas Mercado; Maureen A Smith; Melissa A Carlucci; Kirstie K Danielson; Sirimon Reutrakul Journal: J Clin Sleep Med Date: 2021-08-01 Impact factor: 4.324