Literature DB >> 3166379

Immunoscintigraphy of ovarian endometriosis. A preliminary study.

S H Kennedy1, N D Soper, O A Mojiminiyi, B J Shepstone, D H Barlow.   

Abstract

CA-125 is a membrane antigen detected in the serum of some women with gynaecological disease including endometriosis. We attempted to use a radioiodinated anti-CA-125 monoclonal antibody, OC-125, to image ovarian endometriosis using immunoscintigraphy. Two women with significant endometriosis and normal serum CA-125 levels had positive immunoscintigraphy. In one woman, all areas of endometriosis were imaged; in the other, endometriosis in one affected ovary was seen, but uptake in the other ovary was less than the extent of the disease.

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Year:  1988        PMID: 3166379     DOI: 10.1111/j.1471-0528.1988.tb06532.x

Source DB:  PubMed          Journal:  Br J Obstet Gynaecol        ISSN: 0306-5456


  2 in total

1.  Immunoreactive determinants of CA 125 in women with endometriosis.

Authors:  O A Mojiminiyi; M E Bramwell; S H Kennedy; B J Shepstone; S M Humm; D H Barlow
Journal:  J Clin Pathol       Date:  1989-12       Impact factor: 3.411

2.  Radioimmunoscintigraphy of ovarian tumours with technetium-99m labelled monoclonal antibody-170: first clinical experiences.

Authors:  C Alexander; C E Villena-Heinsen; L Trampert; S Lung-Kurt; E Oberhausen; C M Kirsch; W Schmidt
Journal:  Eur J Nucl Med       Date:  1995-07
  2 in total

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