Victor Johan Bernard Huiskes1, Cornelia Helena Maria van den Ende2, Martine Kruijtbosch3, Hendrik Tinus Ensing4, Marieke Meijs5, Veronique Maria Mathea Meijs6, David Marinus Burger7, Bartholomeus Johannes Fredericus van den Bemt1,7,8. 1. Department of Pharmacy, Sint Maartenskliniek, The Netherlands. 2. Department of Rheumatology, Sint Maartenskliniek, The Netherlands. 3. SIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands. 4. Outpatient Pharmacy, Flevoziekenhuis, Almere, The Netherlands. 5. Outpatient Pharmacy, St. Antonius ziekenhuis Nieuwegein, The Netherlands. 6. Outpatient Pharmacy, LUMC, Leiden, The Netherlands. 7. Department of pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands. 8. Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center +, Maastricht, The Netherlands.
Abstract
AIMS: To assess the effectiveness of medication review on the number of drug-related problems (DRPs) in outpatient cardiology patients. METHODS: In this randomized controlled trial, a computer-assisted and pharmacist-led medication review with patient involvement (questionnaire and telephone call with pharmacist) was conducted in intervention patients prior to their visit to the cardiologist. The control group received usual care. Adult outpatient cardiology patients without support concerning the administration of medication, without a medication review in the past 6 months and who gave permission to access their electronic medication record were included. The primary outcome measure was the number of DRPs 1 month after the visit. Secondary outcome measures concerned the type of DRP and the type of medication involved in the DRPs. RESULTS: In total, 75 patients (mean [standard deviation, SD] age 66.0 [12.5] years, 41% female) were included. Intervention (n = 90) and control group (n = 85) were comparable at baseline. The mean (SD) number of drugs used per patient was 7.9 (3.9). After 1 month, the mean (SD) number of DRPs was 0.3 (0.7) and 0.8 (1.0) and the median (range) number of DRPs was 0 (0-4) and 0 (0-4) in the intervention group and control group, respectively (P < .001). In the intervention group, 74% of the DRPs identified at T0 were solved at T1 vs 14% in the control group. CONCLUSION: This randomized controlled trial suggests that a pharmacist-led medication review in patients with a scheduled visit to the outpatient cardiology clinic decreases the number of DRPs.
RCT Entities:
AIMS: To assess the effectiveness of medication review on the number of drug-related problems (DRPs) in outpatient cardiology patients. METHODS: In this randomized controlled trial, a computer-assisted and pharmacist-led medication review with patient involvement (questionnaire and telephone call with pharmacist) was conducted in intervention patients prior to their visit to the cardiologist. The control group received usual care. Adult outpatient cardiology patients without support concerning the administration of medication, without a medication review in the past 6 months and who gave permission to access their electronic medication record were included. The primary outcome measure was the number of DRPs 1 month after the visit. Secondary outcome measures concerned the type of DRP and the type of medication involved in the DRPs. RESULTS: In total, 75 patients (mean [standard deviation, SD] age 66.0 [12.5] years, 41% female) were included. Intervention (n = 90) and control group (n = 85) were comparable at baseline. The mean (SD) number of drugs used per patient was 7.9 (3.9). After 1 month, the mean (SD) number of DRPs was 0.3 (0.7) and 0.8 (1.0) and the median (range) number of DRPs was 0 (0-4) and 0 (0-4) in the intervention group and control group, respectively (P < .001). In the intervention group, 74% of the DRPs identified at T0 were solved at T1 vs 14% in the control group. CONCLUSION: This randomized controlled trial suggests that a pharmacist-led medication review in patients with a scheduled visit to the outpatient cardiology clinic decreases the number of DRPs.
Authors: Richard Holland; Elizabeth Lenaghan; Ian Harvey; Richard Smith; Lee Shepstone; Alistair Lipp; Maria Christou; David Evans; Christopher Hand Journal: BMJ Date: 2005-01-21
Authors: Denis O'Mahony; David O'Sullivan; Stephen Byrne; Marie Noelle O'Connor; Cristin Ryan; Paul Gallagher Journal: Age Ageing Date: 2014-10-16 Impact factor: 10.668
Authors: Victor Johan Bernard Huiskes; Cornelia Helena Maria van den Ende; Martine Kruijtbosch; Hendrik Tinus Ensing; Marieke Meijs; Veronique Maria Mathea Meijs; David Marinus Burger; Bartholomeus Johannes Fredericus van den Bemt Journal: Br J Clin Pharmacol Date: 2019-12-03 Impact factor: 4.335