Literature DB >> 3165083

Genes on chromosomes 1 and 4 in the mouse are associated with repair of radiation-induced chromatin damage.

M Potter1, K K Sanford, R Parshad, R E Tarone, F M Price, B Mock, K Huppi.   

Abstract

Early-passage skin fibroblasts from different inbred and congenic strains of mice were X-irradiated (1 Gy), and the number of chromatid breaks was determined at 2.0 h after irradiation. The cells from DBA/2N, C3H/HeN, STS/A, C57BL/6N, BALB/cJ, and AKR/N had 25 to 42 chromatid breaks per 100 metaphase cells (efficient repair phenotype). NZB/NJ had greater than 78 and BALB/cAn had 87 to 110 chromatid breaks per 100 cells (inefficient repair phenotype). Differences between BALB/cAn and BALB/c. DBA/2 congenic strains which carry less than 1% of the DBA/2 genome indicate that two genes, one on chromosome 1 linked to bcl-2-Pep-3 and the other on chromosome 4 closely linked to Fv-1, affect the efficiency with which the cells repair radiation-induced chromatin damage.

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Year:  1988        PMID： 3165083     DOI： 10.1016/0888-7543(88)90010-9

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  8 in total

1.  Analysis of the mouse Dhfr/Rep-3 major promoter region by using linker-scanning and internal deletion mutations and DNase I footprinting.

Authors:  M L Smith; P J Mitchell; G F Crouse
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

Review 2.  Mouse chromosome 1.

Authors:  M F Seldin
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  Mouse chromosome 1.

Authors:  M F Seldin; T H Roderick; B Paigen
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression.

Authors:  N C Dracopoli; P Harnett; S J Bale; B Z Stanger; M A Tucker; D E Housman; R F Kefford
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

5.  Differences in the molecular structure of c-myc-activating recombinations in murine plasmacytomas and precursor cells.

Authors:  J R Müller; M Potter; S Janz
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-06       Impact factor: 11.205

6.  Protein-DNA interactions at the major and minor promoters of the divergently transcribed dhfr and rep3 genes during the Chinese hamster ovary cell cycle.

Authors:  J Wells; P Held; S Illenye; N H Heintz
Journal:  Mol Cell Biol       Date:  1996-02       Impact factor: 4.272

Review 7.  Murine models of chronic lymphocytic leukaemia: role of microRNA-16 in the New Zealand Black mouse model.

Authors:  Brian J Scaglione; Erica Salerno; Murugabaskar Balan; Frederick Coffman; Pablo Landgraf; Fatima Abbasi; Sergei Kotenko; Gerald E Marti; Elizabeth S Raveche
Journal:  Br J Haematol       Date:  2007-10-17       Impact factor: 6.998

8.  Sequence and organization of the mouse poly (ADP-ribose) polymerase gene.

Authors:  K Huppi; K Bhatia; D Siwarski; D Klinman; B Cherney; M Smulson
Journal:  Nucleic Acids Res       Date:  1989-05-11       Impact factor: 16.971
  8 in total

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