Literature DB >> 3164800

A new specific chromosomal rearrangement, t(11;20)(p15;q11), in myeloblastic leukemia with maturation.

F Mitelman1, E L Prigogina, E W Fleischman, M A Frenkel, S Garwicz, S Heim, G W Ilyinskaya, U Kristoffersson, N Mandahl, M A Volkova.   

Abstract

The translocation t(11;20)(p15;q11) was found as the sole acquired clonal chromosome abnormality in two patients with acute myeloid leukemia. The bone marrow morphology in both cases corresponded to the M2 subtype of the French-American-British (FAB) classification. None of the patients achieved complete remission, and both died less than 6 months after diagnosis. This particular translocation has not previously been reported in acute nonlymphocytic leukemia.

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Year:  1988        PMID: 3164800

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   11.528


  1 in total

1.  Involvement of the NUP98 gene in a chromosomal translocation t(11;20)(p15;q11.2) in a patient with acute monocytic leukemia (FAB-M5b).

Authors:  N Kakazu; I Shinzato; Y Arai; S Gotoh; A Matsushita; T Ishikawa; K Nagai; T Takahashi; T Ohno; T Tsuchiya; M Ohki; T Abe
Journal:  Int J Hematol       Date:  2001-07       Impact factor: 2.490

  1 in total

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