Literature DB >> 3164630

Moderate antiproliferative effect of the antifolate CB3717 in the BN myeloid leukaemia model.

A A Ermens1, J Lindemans, J Abels.   

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Year:  1988        PMID: 3164630      PMCID: PMC2246555          DOI: 10.1038/bjc.1988.91

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


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  12 in total

1.  Phase II study of a novel antifolate, N10-propargyl-5,8 dideazafolic acid (CB3717), in malignant mesothelioma.

Authors:  B M Cantwell; M Earnshaw; A L Harris
Journal:  Cancer Treat Rep       Date:  1986-11

2.  A method for performing deoxyuridine suppression tests on microtitre plates.

Authors:  J H Matthews; S N Wickramasinghe
Journal:  Clin Lab Haematol       Date:  1986

3.  A potent antitumour quinazoline inhibitor of thymidylate synthetase: synthesis, biological properties and therapeutic results in mice.

Authors:  T R Jones; A H Calvert; A L Jackman; S J Brown; M Jones; K R Harrap
Journal:  Eur J Cancer       Date:  1981-01       Impact factor: 9.162

4.  Interaction of chemotherapeutic agents with methotrexate and 5-fluorouracil and its effect on de novo DNA synthesis.

Authors:  H W Bruckner; C Schreiber; S Waxman
Journal:  Cancer Res       Date:  1975-03       Impact factor: 12.701

5.  Pharmacokinetics of the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB3717) in the mouse.

Authors:  D R Newell; D L Alison; A H Calvert; K R Harrap; M Jarman; T R Jones; M Manteuffel-Cymborowska; P O'Connor
Journal:  Cancer Treat Rep       Date:  1986-08

6.  A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717.

Authors:  A H Calvert; D L Alison; S J Harland; B A Robinson; A L Jackman; T R Jones; D R Newell; Z H Siddik; E Wiltshaw; T J McElwain
Journal:  J Clin Oncol       Date:  1986-08       Impact factor: 44.544

7.  The clinical pharmacokinetics of the novel antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717).

Authors:  D L Alison; D R Newell; C Sessa; S J Harland; L I Hart; K R Harrap; A H Calvert
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

8.  Enhanced therapeutic effect of methotrexate in experimental rat leukemia after inactivation of cobalamin (vitamin B12) by nitrous oxide.

Authors:  A C Kroes; J Lindemans; M Schoester; J Abels
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

9.  Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase.

Authors:  Y C Cheng; G E Dutschman; M C Starnes; M H Fisher; N T Nanavathi; M G Nair
Journal:  Cancer Res       Date:  1985-02       Impact factor: 12.701

10.  Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717.

Authors:  N J Curtin; A L Harris; O F James; M F Bassendine
Journal:  Br J Cancer       Date:  1986-03       Impact factor: 7.640

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