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33 in total

1. Site-directed ligand discovery.

Authors: D A Erlanson; A C Braisted; D R Raphael; M Randal; R M Stroud; E M Gordon; J A Wells
Journal: Proc Natl Acad Sci U S A Date: 2000-08-15 Impact factor: 11.205

2. Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry.

Authors: Yijun Deng; Xilin Zhou; Sita Kugel Desmoulin; Jianmei Wu; Christina Cherian; Zhanjun Hou; Larry H Matherly; Aleem Gangjee
Journal: J Med Chem Date: 2009-05-14 Impact factor: 7.446

3. Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.

Authors: P J Houghton; G S Germain; B J Hazelton; J W Pennington; J A Houghton
Journal: Proc Natl Acad Sci U S A Date: 1989-02 Impact factor: 11.205

4. Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.

Authors: John P Santa Maria; Yumi Park; Lihu Yang; Nicholas Murgolo; Michael D Altman; Paul Zuck; Greg Adam; Chad Chamberlin; Peter Saradjian; Peter Dandliker; Helena I M Boshoff; Clifton E Barry; Charles Garlisi; David B Olsen; Katherine Young; Meir Glick; Elliott Nickbarg; Peter S Kutchukian
Journal: ACS Chem Biol Date: 2017-08-29 Impact factor: 5.100

5. Serial serum AFP heterogeneity changes in patients with hepatocellular carcinoma during chemotherapy.

Authors: P K Buamah; C Cornell; O F James; A W Skillen; A L Harris
Journal: Cancer Chemother Pharmacol Date: 1986 Impact factor: 3.333

6. Novel pyrrolo[2,3-d]pyrimidine antifolate TNP-351: cytotoxic effect on methotrexate-resistant CCRF-CEM cells and inhibition of transformylases of de novo purine biosynthesis.

Authors: F Itoh; O Russello; H Akimoto; G P Beardsley
Journal: Cancer Chemother Pharmacol Date: 1994 Impact factor: 3.333

7. Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.

Authors: Lei Wang; Christina Cherian; Sita Kugel Desmoulin; Lisa Polin; Yijun Deng; Jianmei Wu; Zhanjun Hou; Kathryn White; Juiwanna Kushner; Larry H Matherly; Aleem Gangjee
Journal: J Med Chem Date: 2010-02-11 Impact factor: 7.446

8. Properties influencing the relative binding affinity of pteroate derivatives and drug conjugates thereof to the folate receptor.

Authors: Christopher P Leamon; Fei You; Hari Krishna Santhapuram; Mingjin Fan; Iontcho R Vlahov
Journal: Pharm Res Date: 2009-02-03 Impact factor: 4.200

9. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells.

Authors: Anna Tochowicz; Sean Dalziel; Oliv Eidam; Joseph D O'Connell; Sarah Griner; Janet S Finer-Moore; Robert M Stroud
Journal: J Med Chem Date: 2013-06-21 Impact factor: 7.446

10. Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells.

Authors: C Erlichman; B Mitrovski
Journal: Cancer Chemother Pharmacol Date: 1994 Impact factor: 3.333