| Literature DB >> 31646040 |
Elina A Genina1,2, Alexey N Bashkatov1,2, Daria K Tuchina1,2,3, Polina A Dyachenko Timoshina1,2, Nikita Navolokin4, Alexander Shirokov5, Alexander Khorovodov1, Andrey Terskov1, Maria Klimova1, Aysel Mamedova1, Inna Blokhina1, Ilana Agranovich1, Ekaterina Zinchenko1, Oxana V Semyachkina-Glushkovskaya1, Valery V Tuchin1,2,6.
Abstract
In this paper, measurements of the optical properties (diffuse reflectance, total and collimated transmittance) of brain tissues in healthy rats and rats with C6-glioma were performed in the spectral range from 350 to 1800 nm. Using these measurements, characteristic tissue optical parameters, such as absorption coefficient, scattering coefficient, reduced scattering coefficient, and scattering anisotropy factor were reconstructed. It was obtained that the 10-day development of glioma led to increase of absorption coefficient, which was associated with the water content elevation in the tumor. However, further development of the tumor (formation of the necrotic core) led to decrease in the water content. The dependence of the scattering properties on the different stages of model glioma development was more complex. Light penetration depth into the healthy and tumor brain was evaluated.Entities:
Year: 2019 PMID： 31646040 PMCID： PMC6788608 DOI： 10.1364/BOE.10.005182
Source DB: PubMed Journal: Biomed Opt Express ISSN： 2156-7085 Impact factor: 3.732