Literature DB >> 31634674

Transgenerational epigenetic inheritance: from phenomena to molecular mechanisms.

Noa Liberman1, Simon Yuan Wang1, Eric Lieberman Greer2.   

Abstract

Inherited information not encoded in the DNA sequence can regulate a variety of complex phenotypes. However, how this epigenetic information escapes the typical epigenetic erasure that occurs upon fertilization and how it regulates behavior is still unclear. Here we review recent examples of brain related transgenerational epigenetic inheritance and delineate potential molecular mechanisms that could regulate how non-genetic information could be transmitted.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Year:  2019        PMID： 31634674      PMCID： PMC6889819          DOI： 10.1016/j.conb.2019.09.012

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  334 in total

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  13 in total

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