Literature DB >> 31629161

"How do we rally around the one who was positive?" Familial uncertainty management in the context of men managing BRCA-related cancer risks.

Emily A Rauscher1, Marleah Dean2, Gemme Campbell-Salome3, Joshua B Barbour4.   

Abstract

RATIONALE: Men with BRCA-related cancer risks face increased disease risk as well as the prospect of passing on their risk to children.
OBJECTIVE: This study investigates men's communicative appraisal and management of uncertainty related to BRCA-related cancer risks and decision-making.
METHODS: Guided by uncertainty management theory (UMT), a directed content analysis approach was utilized to analyze interviews with 25 men who either carry a pathogenic BRCA variant or have a 50% chance of carrying a variant but have not yet been tested.
RESULTS: Participants appraised their individual uncertainty as irrelevant or dangerous but appraised their familial uncertainty as dangerous. Men appraising their uncertainty as a danger exhibited more proactive information seeking healthcare behaviors-such as genetic testing and following recommended screenings-than men who appraised their uncertainty as irrelevant. Participants appraised familial uncertainty as a danger and were engaged in information management with family members, as well as encouraging family members to engage in proactive healthcare decision-making.
CONCLUSIONS: Men with BRCA-related cancer risks lack understanding about their risks and how to manage them. Increased attention should be paid to the development of interventions tailored specifically to men. Further, interventions focusing on strategically developing proactive family communication behaviors would also be beneficial to men and their families.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  BRCA1/2; Communication; Family; Hereditary cancer risk; Uncertainty; Uncertainty management theory

Year:  2019        PMID: 31629161     DOI: 10.1016/j.socscimed.2019.112592

Source DB:  PubMed          Journal:  Soc Sci Med        ISSN: 0277-9536            Impact factor:   4.634


  10 in total

Review 1.  A Case-Based Clinical Approach to the Investigation, Management and Screening of Families with BRCA2 Related Prostate Cancer.

Authors:  Bradley King; Jana McHugh; Katie Snape
Journal:  Appl Clin Genet       Date:  2021-05-20

2.  Sharing genetic test results with family members of BRCA, PALB2, CHEK2, and ATM carriers.

Authors:  Marleah Dean; Ann L Tezak; Sabrina Johnson; Joy K Pierce; Anne Weidner; Kate Clouse; Tuya Pal; Deborah Cragun
Journal:  Patient Educ Couns       Date:  2021-01-05

3.  Engaging Men With BRCA-Related Cancer Risks: Practical Advice for BRCA Risk Management From Male Stakeholders.

Authors:  Marleah Dean; Gemme Campbell-Salome; Emily A Rauscher
Journal:  Am J Mens Health       Date:  2020 May-Jun

4.  Care of men with cancer-predisposing BRCA variants.

Authors:  Rachel Horton; Paul Pharoah; Judith Hayward; Anneke Lucassen
Journal:  BMJ       Date:  2021-10-14

5.  Understanding the Information Needs of Patients With Ovarian Cancer Regarding Genetic Testing to Inform Intervention Design: Interview Study.

Authors:  Yan Zhang; Siqi Yi; Ciaran B Trace; Marian Yvette Williams-Brown
Journal:  JMIR Cancer       Date:  2022-02-08

6.  A randomized controlled trial comparing self-referred message to family-referred message promoting men's adherence to evidence-based guidelines on BRCA1/2 germline genetic testing: A registered study protocol.

Authors:  Serena Petrocchi; Giulia Ongaro; Mariarosaria Calvello; Irene Feroce; Bernardo Bonanni; Gabriella Pravettoni
Journal:  PLoS One       Date:  2022-04-08       Impact factor: 3.240

7.  Investigating men's motivations to engage in genetic screening for BRCA1 and BRCA2 mutations.

Authors:  Anna Maria Annoni; Claudia Longhini
Journal:  PLoS One       Date:  2022-03-18       Impact factor: 3.240

8.  Patient experiences align with the familial hypercholesterolemia global call to action.

Authors:  Laney K Jones; Nicole Walters; Andrew Brangan; Catherine D Ahmed; Katherine A Wilemon; Gemme Campbell-Salome; Alanna K Rahm; Samuel S Gidding; Amy C Sturm
Journal:  Am J Prev Cardiol       Date:  2022-04-18

9.  Psychological Determinants of Men's Adherence to Cascade Screening for BRCA1/2.

Authors:  Giulia Ongaro; Serena Petrocchi; Mariarosaria Calvello; Bernardo Bonanni; Irene Feroce; Gabriella Pravettoni
Journal:  Curr Oncol       Date:  2022-04-02       Impact factor: 3.109

10.  Motivating cascade testing for familial hypercholesterolemia: applying the extended parallel process model for clinician communication.

Authors:  Gemme Campbell-Salome; Nicole L Walters; Ilene G Ladd; Amanda Sheldon; Catherine Davis Ahmed; Andrew Brangan; Megan N McMinn; Alanna K Rahm; Marci L B Schwartz; Eric Tricou; Carla L Fisher; Amy C Sturm
Journal:  Transl Behav Med       Date:  2022-07-18       Impact factor: 3.626

  10 in total

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