Literature DB >> 3162781

Ofloxacin, a new quinolone for the treatment of gonorrhea.

M K Rajakumar1, Y F Ngeow, B S Khor, K F Lim.   

Abstract

Forty-three patients with uncomplicated gonorrhea were treated with 400 mg of ofloxacin. All had cultures negative for Neisseria gonorrhoeae at follow-up within two weeks of treatment. Minimal side effects were reported. Ofloxacin appears to be satisfactory as a single-dose oral drug for the treatment of gonococcal urethritis, including those cases caused by penicillinase-producing strains of N. gonorrhoeae.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3162781     DOI： 10.1097/00007435-198801000-00005

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN： 0148-5717            Impact factor:   2.830


  11 in total

1.  Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains.

Authors:  J M Covino; M Cummings; B Smith; S Benes; K Draft; W M McCormack
Journal:  Antimicrob Agents Chemother       Date:  1990-01       Impact factor: 5.191

2.  Penicillinase-producing Neisseria gonorrhoeae strains in east Black Sea region of Turkey.

Authors:  I Köksal; G Ozgür; B Piskin
Journal:  Infection       Date:  1990 Nov-Dec       Impact factor: 3.553

Review 3.  A Brief History of Evolving Diagnostics and Therapy for Gonorrhea: Lessons Learned.

Authors:  Edward W Hook; Robert D Kirkcaldy
Journal:  Clin Infect Dis       Date:  2018-09-28       Impact factor: 9.079

Review 4.  Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use.

Authors:  P A Todd; D Faulds
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

Review 5.  Antibiotic treatment of gonorrhoea--clinical evidence for choice.

Authors:  C Bignell
Journal:  Genitourin Med       Date:  1996-10

Review 6.  Quinolone antibacterial agents for the treatment of genitourinary tract infections.

Authors:  T J Babinchak; R J Fass
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-12       Impact factor: 3.267

7.  Low dose oral ofloxacin to treat gonorrhoea in Hong Kong.

Authors:  B J Heap
Journal:  Genitourin Med       Date:  1989-06

8.  Multicenter randomized study of single-dose ofloxacin versus amoxicillin-probenecid for treatment of uncomplicated gonococcal infection.

Authors:  J R Black; J M Long; B E Zwickl; B S Ray; M S Verdon; S Wetherby; E W Hook; H H Handsfield
Journal:  Antimicrob Agents Chemother       Date:  1989-02       Impact factor: 5.191

9.  Effectiveness of norfloxacin and ofloxacin for treatment of gonorrhoea and decrease of in vitro susceptibility to quinolones over time in Rwanda.

Authors:  J Bogaerts; W M Tello; J Akingeneye; V Mukantabana; E Van Dyck; P Piot
Journal:  Genitourin Med       Date:  1993-06

Review 10.  The use of fluoroquinolones in sexually transmitted diseases in Southeast Asia.

Authors:  A Sivayathorn
Journal:  Drugs       Date:  1995       Impact factor: 9.546
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.