Literature DB >> 31602184

The Impact of Sacral Neuromodulation on Sexual Dysfunction.

Pedro Simoes de Oliveira1, José Palma Reis1, Tiago Ribeiro de Oliveira1, David Martinho1, Ricardo Pereira E Silva1, Joao Marcelino1, Sandro Gaspar1, Francisco Martins1, Tome Lopes1.   

Abstract

BACKGROUND/AIMS: Sacral neuromodulation (SNM) is a well-established treatment in several urinary and bowel dysfunctions, nevertheless its role on sexual dysfunction remains unclear. We evaluate the impact of SNM on sexual function and its association with age at SNM, functional diagnosis and post-void residual urine (PVR) before SNM.
METHODS: Patients who had SNM were retrospectively analyzed. Sexual function was assessed before and after treatment with the International Index of Erectile Function (IIEF-5) for men and the Female Sexual Function Index (FSFI) for women. IIEF-5 and FSFI were also associated with age at SNM, functional diagnosis, and PVR.
RESULTS: Fifteen females and 9 males, with a median age of 41 years (26-72 years), median follow-up 20.7 months (2-53 months) were enrolled. IIEF-5 improved in 4 patients (p = 0.06), and FSFI total score in 5 (p = 0.2). There was significant association between functional diagnosis and FSFI total score (p = 0.05), and FSFI specific domains of arousal (p = 0.03), lubrication (p = 0.04), and satisfaction (p = 0.03), with significant improvement showed in patients with detrusor overactivity with impaired contractility.
CONCLUSION: Although gains observed in IIEF-5 and FSFI were modest, our preliminary results show that SNM may have favorable impact on sexual function.
Copyright © 2019 by S. Karger AG, Basel.

Entities:  

Keywords:  Lubrication; Parasympathetic nervous system; Sacral neuromodulation; Sexual dysfunction

Year:  2019        PMID: 31602184      PMCID: PMC6738141          DOI: 10.1159/000499307

Source DB:  PubMed          Journal:  Curr Urol        ISSN: 1661-7649


  26 in total

Review 1.  Recent advances in women's sexual function and dysfunction.

Authors:  Rosemary Basson
Journal:  Menopause       Date:  2004 Nov-Dec       Impact factor: 2.953

2.  Economic evaluation of sacral neuromodulation in overactive bladder: A Canadian perspective.

Authors:  Magdy M Hassouna; Hamid Sadri
Journal:  Can Urol Assoc J       Date:  2015 Jul-Aug       Impact factor: 1.862

Review 3.  The anatomy of the distal vagina: towards unity.

Authors:  Helen E O'Connell; Norm Eizenberg; Marzia Rahman; Joan Cleeve
Journal:  J Sex Med       Date:  2008-06-28       Impact factor: 3.802

Review 4.  A Joint Mechanism of Action for Sacral Neuromodulation for Bladder and Bowel Dysfunction?

Authors:  James Jones; Dirk Van de Putte; Dirk De Ridder; Charles Knowles; Ronan O'Connell; Dwight Nelson; An-Sofie Goessaert; Karel Everaert
Journal:  Urology       Date:  2016-05-24       Impact factor: 2.649

5.  Real-Time Changes in Brain Activity during Sacral Neuromodulation for Overactive Bladder.

Authors:  Bradley C Gill; Javier Pizarro-Berdichevsky; Pallab K Bhattacharyya; Thaddeus S Brink; Brian K Marks; Adrienne Quirouet; Sandip P Vasavada; Stephen E Jones; Howard B Goldman
Journal:  J Urol       Date:  2017-06-20       Impact factor: 7.450

6.  Effect of sacral neuromodulation for faecal incontinence on sexual activity.

Authors:  M E D Jarrett; R J Nicholls; M A Kamm
Journal:  Colorectal Dis       Date:  2005-09       Impact factor: 3.788

Review 7.  Clinical autonomic neurophysiology and the male sexual response: an overview.

Authors:  Claire C Yang; Xiaogang Jiang
Journal:  J Sex Med       Date:  2009-03       Impact factor: 3.802

8.  Troubleshooting sacral neuromodulation issues.

Authors:  Maude E Carmel; Sandip P Vasavada; Howard B Goldman
Journal:  Curr Urol Rep       Date:  2012-10       Impact factor: 3.092

9.  Clinical female sexual outcome after sacral neuromodulation implant for lower urinary tract symptom (LUTS).

Authors:  Giuseppe Lombardi; Nicola Mondaini; Angelo Macchiarella; Antonio Cilotti; Giulio Del Popolo
Journal:  J Sex Med       Date:  2008-03-26       Impact factor: 3.802

10.  Predictors of reoperation after sacral neuromodulation: A single institution evaluation of over 400 patients.

Authors:  Kenneth M Peters; Kim A Killinger; Jason P Gilleran; Jamie Bartley; Cheryl Wolfert; Judith A Boura
Journal:  Neurourol Urodyn       Date:  2015-11-20       Impact factor: 2.696

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