Literature DB >> 18373528

Clinical female sexual outcome after sacral neuromodulation implant for lower urinary tract symptom (LUTS).

Giuseppe Lombardi1, Nicola Mondaini, Angelo Macchiarella, Antonio Cilotti, Giulio Del Popolo.   

Abstract

INTRODUCTION: Over the last few years, sacral neuromodulation (SNM) has become an established treatment option for lower urinary tract symptoms (LUTS). AIM: To evaluate if SNM improves sexual function in females treated with SNM for LUTS. MAIN OUTCOME MEASURES: Improvement in sexuality by the Female Sexual Function Index (FSFI) and the Female Sexual Distress Score (FSDS).
MATERIALS AND METHODS: We included 31 women, 17 of whom were neurogenic with permanent SNM. Prior to the neuromodulation screening, we assessed sexual function through blood sexual hormones, the FSFI and the FSDS questionnaires. Significant enhancement in sexuality meant an increase of 60% of the total score or of one FSFI domain, or 50% improvement on the FSDS. Only females who showed significant benefits in the first visit post-permanent SNM repeated the questionnaires in follow-up. All these women had their final visit by July 2007.
RESULTS: Both questionnaires indicated a clinically significant improvement in sexuality that was maintained up to the final visit for 4 out of 11 neurogenics with sexual dysfunctions: one showed arousal and desire disorders, one showed arousal disorder and lubrication impairment, one showed arousal disorder and pain, and one showed desire and orgasm deficits. Mean duration of sexual improvement was 23 months. Notable clinical improvement in sexuality was observed in two out of eight idiopathics (one suffering from arousal and desire disorders, and one from lubrication impairment) with a median follow-up of 22 months.
CONCLUSIONS: The positive effects regarding sexuality may be due either to enhancement of LUTS or to the direct stimulation of the sacral roots (S3).

Entities:  

Mesh:

Year:  2008        PMID: 18373528     DOI: 10.1111/j.1743-6109.2008.00812.x

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  9 in total

Review 1.  Sacral neuromodulation and female sexuality.

Authors:  Giuseppe Lombardi; Enrico Finazzi Agrò; Giulio Del Popolo
Journal:  Int Urogynecol J       Date:  2015-04-16       Impact factor: 2.894

Review 2.  Sacral neuromodulation stimulation for IC/PBS, chronic pelvic pain, and sexual dysfunction.

Authors:  Jennifer Yonaitis Fariello; K Whitmore
Journal:  Int Urogynecol J       Date:  2010-12       Impact factor: 2.894

Review 3.  Role of sacral neuromodulation in modern urogynaecology practice: a review of recent literature.

Authors:  Samina Tahseen
Journal:  Int Urogynecol J       Date:  2018-01-04       Impact factor: 2.894

Review 4.  Treatments for erectile dysfunction in spinal cord patients: alternatives to phosphodiesterase type 5 inhibitors? A review study.

Authors:  G Lombardi; S Musco; J J Wyndaele; G Del Popolo
Journal:  Spinal Cord       Date:  2015-07-21       Impact factor: 2.772

5.  The Impact of Sacral Neuromodulation on Sexual Dysfunction.

Authors:  Pedro Simoes de Oliveira; José Palma Reis; Tiago Ribeiro de Oliveira; David Martinho; Ricardo Pereira E Silva; Joao Marcelino; Sandro Gaspar; Francisco Martins; Tome Lopes
Journal:  Curr Urol       Date:  2019-07-20

6.  Refractory Sexual Arousal Subsequent to Sacral Neuromodulation.

Authors:  Dani Zoorob; Amanda S Deis; Kathryn Lindsay
Journal:  Case Rep Obstet Gynecol       Date:  2019-04-02

7.  Transcutaneous Electrical Nerve Stimulation to Improve Female Sexual Dysfunction Symptoms: A Pilot Study.

Authors:  Lauren L Zimmerman; Priyanka Gupta; Florence O'Gara; Nicholas B Langhals; Mitchell B Berger; Tim M Bruns
Journal:  Neuromodulation       Date:  2018-09-03

8.  Effect of sacral neuromodulation on female sexual function and quality of life: Are they correlated?

Authors:  Mai Banakhar; Yahya Gazwani; Mohamed El Kelini; Tariq Al-Shaiji; Magdy Hassouna
Journal:  Can Urol Assoc J       Date:  2014-11       Impact factor: 1.862

9.  Sacral neuromodulation for the treatment of neurogenic lower urinary tract dysfunction caused by multiple sclerosis: a single-centre prospective series.

Authors:  Daniel S Engeler; Daniel Meyer; Dominik Abt; Stefanie Müller; Hans-Peter Schmid
Journal:  BMC Urol       Date:  2015-10-23       Impact factor: 2.264

  9 in total

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