Literature DB >> 3159490

Activity of esterase in the hydrolysis of 3',5'-diesters of 5-fluoro-2'-deoxyuridine in relation to the structure of the diester prodrugs.

T Kawaguchi, Y Suzuki, Y Nakahara, N Nambu, T Nagai.   

Abstract

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Year:  1985        PMID： 3159490     DOI： 10.1248/cpb.33.301

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


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  4 in total

1.  Selection of a derivative of the antiviral agent 9-[(1,3-dihydroxy-2-propoxy)-methyl]guanine (DHPG) with improved oral absorption.

Authors:  E J Benjamin; B A Firestone; R Bergstrom; M Fass; I Massey; I Tsina; Y Y Lin
Journal:  Pharm Res       Date:  1987-04       Impact factor: 4.200

2.  Nonenzymatic and enzymatic hydrolysis of 5-fluoro-2'-deoxyuridine (FUdR) esters.

Authors:  T Kawaguchi; S Fukushima; Y Hayashi; M Nakano
Journal:  Pharm Res       Date:  1988-11       Impact factor: 4.200

3.  Chemical and enzymatic degradation of ganciclovir prodrugs: enhanced stability of the diadamantoate prodrug under acid conditions.

Authors:  M F Powell; A Magill; N Chu; K Hama; C I Mau; L Foster; R Bergstrom
Journal:  Pharm Res       Date:  1991-11       Impact factor: 4.200

4.  Structure-metabolism relationships in the hydrolysis of nicotinate esters by rat liver and brain subcellular fractions.

Authors:  A Durrer; B Walther; A Racciatti; G Boss; B Testa
Journal:  Pharm Res       Date:  1991-07       Impact factor: 4.200
  4 in total

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