Literature DB >> 3158673

Lymphocyte subpopulations in patients with hydroxocobalamin responsive megaloblastic anaemia.

M A Wodzinski, M J Forrest, D Barnett, A C Lawrence.   

Abstract

Lymphocyte subpopulations and intrinsic factor and gastric parietal cell antibodies have been measured in 23 patients with megaloblastic anaemia who responded to treatment with hydroxocobalamin. The ratio of helper (OKT4) to suppressor (OKT8) lymphocytes was significantly increased in patients with intrinsic factor antibody compared with those who lacked the antibody. No such correlation was found for gastric parietal cell antibody. Alterations in the lymphocyte helper to suppressor (OKT4:OKT8) ratio may be associated with pernicious anaemia.

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Year:  1985        PMID： 3158673      PMCID： PMC499214          DOI： 10.1136/jcp.38.5.582

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  5 in total

1.  Enumeration of T lymphocytes subsets in autoimmune disease using monoclonal antibodies.

Authors:  F Raeman; W De Cock; T De Beukelaar; J De Cree; H Verhaegen
Journal:  Clin Exp Immunol       Date:  1981-09       Impact factor: 4.330

Review 2.  The use of monoclonal anti-T cell antibodies to study T cell imbalances in human diseases.

Authors:  M A Bach; J F Bach
Journal:  Clin Exp Immunol       Date:  1981-09       Impact factor: 4.330

3.  Lymphocyte subpopulations in pernicious anemia.

Authors:  N Imamura; K Fujimura; A Kuramoto
Journal:  N Engl J Med       Date:  1984-07-05       Impact factor: 91.245

Review 4.  Current concepts in immunology: Regulation of the immune response--inducer and suppressor T-lymphocyte subsets in human beings.

Authors:  E L Reinherz; S F Schlossman
Journal:  N Engl J Med       Date:  1980-08-14       Impact factor: 91.245

5.  Gastric mucosal lymphocyte subpopulations in pernicious anemia and in normal stomach.

Authors:  M D Kaye; P J Whorwell; R Wright
Journal:  Clin Immunol Immunopathol       Date:  1983-09
  5 in total
  5 in total

1.  Peripheral blood lymphocyte subpopulations in patients with primary proliferative and secondary polycythaemia.

Authors:  J T Wilde; D Barnett; M J Forrest; A C Lawrence
Journal:  J Clin Pathol       Date:  1987-02       Impact factor: 3.411

2.  Longitudinal study of circulating gastric antibodies in pernicious anaemia.

Authors:  R J Davidson; H I Atrah; H F Sewell
Journal:  J Clin Pathol       Date:  1989-10       Impact factor: 3.411

3.  Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment.

Authors:  J Tamura; K Kubota; H Murakami; M Sawamura; T Matsushima; T Tamura; T Saitoh; H Kurabayshi; T Naruse
Journal:  Clin Exp Immunol       Date:  1999-04       Impact factor: 4.330

4.  Lymphocyte surface phenotypes in pernicious anemia.

Authors:  R Carmel; D Boone; J W Parker
Journal:  Dig Dis Sci       Date:  1987-08       Impact factor: 3.199

5.  Functional defect of T cells in autoimmune gastritis.

Authors:  J A Vargas; M Alvarez-Mon; L Manzano; A Albillos; A Fernandez-Corugedo; F Albarrán; A Durántez
Journal:  Gut       Date:  1995-02       Impact factor: 23.059
  5 in total

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