Franz Wegner1, Thomas Friedrich2, Anselm von Gladiss2, Ulrike Grzyska3, Malte M Sieren3, Kerstin Lüdtke-Buzug2, Alex Frydrychowicz3, Thorsten M Buzug2, Jörg Barkhausen3, Julian Haegele4. 1. Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany. franz.wegner@uksh.de. 2. Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany. 3. Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany. 4. Zentrum für Radiologie und Nuklearmedizin, Von-Werth-Straße 5, 41515, Grevenbroich, Germany.
Abstract
PURPOSE: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). MATERIALS AND METHODS: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3-4 mm; length: 11-38 mm) and materials (stainless steel, platinum-chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. RESULTS: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. CONCLUSION: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.
PURPOSE: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). MATERIALS AND METHODS: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3-4 mm; length: 11-38 mm) and materials (stainless steel, platinum-chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. RESULTS: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. CONCLUSION: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.
Entities:
Keywords:
Artifacts; Computed tomography; Magnetic particle imaging; Magnetic resonance imaging; Stents
Authors: Franz Wegner; Kerstin Lüdtke-Buzug; Sjef Cremers; Thomas Friedrich; Malte M Sieren; Julian Haegele; Martin A Koch; Emine U Saritas; Paul Borm; Thorsten M Buzug; Joerg Barkhausen; Mandy Ahlborg Journal: Nanomaterials (Basel) Date: 2022-05-21 Impact factor: 5.719
Authors: Franz Wegner; Anselm von Gladiss; Julian Haegele; Ulrike Grzyska; Malte Maria Sieren; Erik Stahlberg; Thekla Helene Oechtering; Kerstin Lüdtke-Buzug; Joerg Barkhausen; Thorsten M Buzug; Thomas Friedrich Journal: Int J Nanomedicine Date: 2021-01-11