Literature DB >> 31576587

SIVcpz cross-species transmission and viral evolution toward HIV-1 in a humanized mouse model.

James Curlin1, Kimberly Schmitt1, Leila Remling-Mulder1, Ryan Moriarty2, Mark Stenglein1, Shelby O'Connor2, Preston Marx3,4, Ramesh Akkina1.   

Abstract

HIV-1 evolved from its progenitor SIV strains, but details are lacking on its adaptation to the human host. We followed the evolution of SIVcpz in humanized mice to mimic cross-species transmission. Increasing viral loads, CD4+ T-cell decline, and non-synonymous mutations were seen in the entire genome reflecting viral adaptation.
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  SIVcpz evolution into HIV-1; SIVcpz pathogenesis in humanized mice; cross-species transmission of SIV; modeling SIV evolution using humanized mice; viral evolution of SIVcpzEK505 into HIV-1

Mesh：

Year:  2019        PMID： 31576587      PMCID： PMC6942238          DOI： 10.1111/jmp.12440

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  28 in total

1.  Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo.

Authors:  J Bai; S Gorantla; N Banda; L Cagnon; J Rossi; R Akkina
Journal:  Mol Ther       Date:  2000-03       Impact factor: 11.454

2.  Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

Authors:  Michael W Melkus; Jacob D Estes; Angela Padgett-Thomas; Joel Gatlin; Paul W Denton; Florence A Othieno; Anja K Wege; Ashley T Haase; J Victor Garcia
Journal:  Nat Med       Date:  2006-10-22       Impact factor: 53.440

3.  Modeling the evolution of SIV sooty mangabey progenitor virus towards HIV-2 using humanized mice.

Authors:  Kimberly Schmitt; Dipu Mohan Kumar; James Curlin; Leila Remling-Mulder; Mark Stenglein; Shelby O'Connor; Preston Marx; Ramesh Akkina
Journal:  Virology       Date:  2017-07-24       Impact factor: 3.616

4.  Serial human passage of simian immunodeficiency virus by unsterile injections and the emergence of epidemic human immunodeficiency virus in Africa.

Authors:  P A Marx; P G Alcabes; E Drucker
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-06-29       Impact factor: 6.237

5.  Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

Authors:  Joshua Quick; Nathan D Grubaugh; Steven T Pullan; Ingra M Claro; Andrew D Smith; Karthik Gangavarapu; Glenn Oliveira; Refugio Robles-Sikisaka; Thomas F Rogers; Nathan A Beutler; Dennis R Burton; Lia Laura Lewis-Ximenez; Jaqueline Goes de Jesus; Marta Giovanetti; Sarah C Hill; Allison Black; Trevor Bedford; Miles W Carroll; Marcio Nunes; Luiz Carlos Alcantara; Ester C Sabino; Sally A Baylis; Nuno R Faria; Matthew Loose; Jared T Simpson; Oliver G Pybus; Kristian G Andersen; Nicholas J Loman
Journal:  Nat Protoc       Date:  2017-05-24       Impact factor: 13.491

Review 6.  Humanized mice: current states and perspectives.

Authors:  Sylvie Garcia; Antonio A Freitas
Journal:  Immunol Lett       Date:  2012-04-09       Impact factor: 3.685

Review 7.  Human immune responses and potential for vaccine assessment in humanized mice.

Authors:  Ramesh Akkina
Journal:  Curr Opin Immunol       Date:  2013-04-27       Impact factor: 7.486

Review 8.  Humanized mouse models of HIV infection.

Authors:  Paul W Denton; J Víctor García
Journal:  AIDS Rev       Date:  2011 Jul-Sep       Impact factor: 2.500

Review 9.  Current advances in humanized mouse models.

Authors:  Ryoji Ito; Takeshi Takahashi; Ikumi Katano; Mamoru Ito
Journal:  Cell Mol Immunol       Date:  2012-02-13       Impact factor: 11.530

10.  Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse.

Authors:  R K Akkina; J D Rosenblatt; A G Campbell; I S Chen; J A Zack
Journal:  Blood       Date:  1994-09-01       Impact factor: 22.113
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  5 in total

1.  Mimicking SIV chimpanzee viral evolution toward HIV-1 during cross-species transmission.

Authors:  Kimberly Schmitt; James Curlin; Leila Remling-Mulder; Ryan Moriarty; Kelly Goff; Shelby O'Connor; Mark Stenglein; Preston Marx; Ramesh Akkina
Journal:  J Med Primatol       Date:  2020-08-17       Impact factor: 0.667

2.  Evolution of SIVsm in humanized mice towards HIV-2.

Authors:  James Curlin; Kimberly Schmitt; Leila Remling-Mulder; Ryan Moriarty; Kelly Goff; Shelby O'Connor; Mark Stenglein; Preston Marx; Ramesh Akkina
Journal:  J Med Primatol       Date:  2020-08-10       Impact factor: 0.667

3.  Evolution of SIVmac239 following serial passaging in humanized mice.

Authors:  James Z Curlin; Kimberly Schmitt; Leila Remling-Mulder; Jared Morrison; John J Baczenas; Corina Valencia Tibbits; Kelly Goff; Shelby O'Connor; Mark Stenglein; Preston Marx; Ramesh Akkina
Journal:  J Med Primatol       Date:  2022-08-28       Impact factor: 0.821

4.  Long-term evolutionary adaptation of SIVcpz toward HIV-1 using a humanized mouse model.

Authors:  Kimberly Schmitt; James Curlin; Leila Remling-Mulder; Jared Morrison; Ryan Moriarty; Kelly Goff; Mark Stenglein; Shelby O'Connor; Preston Marx; Ramesh Akkina
Journal:  J Med Primatol       Date:  2022-08-28       Impact factor: 0.821

5.  Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice.

Authors:  Kimberly Schmitt; James Curlin; Leila Remling-Mulder; Ryan Moriarty; Kelly Goff; Shelby O'Connor; Mark Stenglein; Preston Marx; Ramesh Akkina
Journal:  Front Microbiol       Date:  2020-08-11       Impact factor: 5.640
  5 in total

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