Literature DB >> 32777101

Evolution of SIVsm in humanized mice towards HIV-2.

James Curlin1, Kimberly Schmitt1, Leila Remling-Mulder1, Ryan Moriarty2, Kelly Goff3, Shelby O'Connor2, Mark Stenglein1, Preston Marx3,4, Ramesh Akkina1.   

Abstract

Through the accumulation of adaptive mutations, HIV-2 originated from SIVsm. To identify these evolutionary changes, a humanized mouse model recapitulated the process that likely enabled this cross-species transmission event. Various adaptive mutations arose, as well as increased virulence and CD4+ T-cell decline as the virus was passaged in humanized mice.
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  HIV-2 viral evolution; SIVsm evolution towards HIV-2; SIVsm infection in humanized mice; Sooty Mangabeys; cross-species SIV transmission; hu-HSC mice for viral cross-species jump

Year:  2020        PMID： 32777101      PMCID： PMC8162839          DOI： 10.1111/jmp.12486

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  22 in total

1.  Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo.

Authors:  J Bai; S Gorantla; N Banda; L Cagnon; J Rossi; R Akkina
Journal:  Mol Ther       Date:  2000-03       Impact factor: 11.454

2.  An African primate lentivirus (SIVsm) closely related to HIV-2.

Authors:  V M Hirsch; R A Olmsted; M Murphey-Corb; R H Purcell; P R Johnson
Journal:  Nature       Date:  1989-06-01       Impact factor: 49.962

3.  Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

Authors:  Joshua Quick; Nathan D Grubaugh; Steven T Pullan; Ingra M Claro; Andrew D Smith; Karthik Gangavarapu; Glenn Oliveira; Refugio Robles-Sikisaka; Thomas F Rogers; Nathan A Beutler; Dennis R Burton; Lia Laura Lewis-Ximenez; Jaqueline Goes de Jesus; Marta Giovanetti; Sarah C Hill; Allison Black; Trevor Bedford; Miles W Carroll; Marcio Nunes; Luiz Carlos Alcantara; Ester C Sabino; Sally A Baylis; Nuno R Faria; Matthew Loose; Jared T Simpson; Oliver G Pybus; Kristian G Andersen; Nicholas J Loman
Journal:  Nat Protoc       Date:  2017-05-24       Impact factor: 13.491

Review 4.  Humanized mice: current states and perspectives.

Authors:  Sylvie Garcia; Antonio A Freitas
Journal:  Immunol Lett       Date:  2012-04-09       Impact factor: 3.685

Review 5.  Humanized mouse models of HIV infection.

Authors:  Paul W Denton; J Víctor García
Journal:  AIDS Rev       Date:  2011 Jul-Sep       Impact factor: 2.500

Review 6.  Origins of HIV and the AIDS pandemic.

Authors:  Paul M Sharp; Beatrice H Hahn
Journal:  Cold Spring Harb Perspect Med       Date:  2011-09       Impact factor: 6.915

7.  Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Côte d'Ivoire.

Authors:  Ahidjo Ayouba; Chantal Akoua-Koffi; Sébastien Calvignac-Spencer; Amandine Esteban; Sabrina Locatelli; Hui Li; Yingying Li; Beatrice H Hahn; Eric Delaporte; Fabian H Leendertz; Martine Peeters
Journal:  AIDS       Date:  2013-09-24       Impact factor: 4.177

8.  Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.

Authors:  Ramesh Akkina; Atef Allam; Alejandro B Balazs; Joel N Blankson; John C Burnett; Sofia Casares; J Victor Garcia; Kim J Hasenkrug; Fatah Kashanchi; Scott G Kitchen; Florian Klein; Priti Kumar; Andrew D Luster; Larisa Y Poluektova; Mangala Rao; Brigitte E Sanders-Beer; Leonard D Shultz; Jerome A Zack
Journal:  AIDS Res Hum Retroviruses       Date:  2016-02       Impact factor: 2.205

9.  Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse.

Authors:  R K Akkina; J D Rosenblatt; A G Campbell; I S Chen; J A Zack
Journal:  Blood       Date:  1994-09-01       Impact factor: 22.113

10.  LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.

Authors:  Andreas Wilm; Pauline Poh Kim Aw; Denis Bertrand; Grace Hui Ting Yeo; Swee Hoe Ong; Chang Hua Wong; Chiea Chuen Khor; Rosemary Petric; Martin Lloyd Hibberd; Niranjan Nagarajan
Journal:  Nucleic Acids Res       Date:  2012-10-12       Impact factor: 16.971
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  2 in total

1.  Evolution of SIVmac239 following serial passaging in humanized mice.

Authors:  James Z Curlin; Kimberly Schmitt; Leila Remling-Mulder; Jared Morrison; John J Baczenas; Corina Valencia Tibbits; Kelly Goff; Shelby O'Connor; Mark Stenglein; Preston Marx; Ramesh Akkina
Journal:  J Med Primatol       Date:  2022-08-28       Impact factor: 0.821

2.  Long-term evolutionary adaptation of SIVcpz toward HIV-1 using a humanized mouse model.

Authors:  Kimberly Schmitt; James Curlin; Leila Remling-Mulder; Jared Morrison; Ryan Moriarty; Kelly Goff; Mark Stenglein; Shelby O'Connor; Preston Marx; Ramesh Akkina
Journal:  J Med Primatol       Date:  2022-08-28       Impact factor: 0.821
  2 in total

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