| Literature DB >> 31554470 |
Filippo Calanna1, Foster Chen2, Salvatore Risitano2, John S Vorhies2, Massimo Franceschini1, Nicholas J Giori2, Pier Francesco Indelli2.
Abstract
We describe a modified surgical technique developed to enhance the classical irrigation and debridement procedure to improve the possibilities of retaining an infected total knee arthroplasty. This technique, debridement antibiotic pearls and retention of the implant (DAPRI), aims to remove the intra-articular biofilm allowing a higher and prolonged local antibiotic concentration using calcium sulfate beads. The combination of three different surgical techniques (methylene blue staining, argon beam electrical stimulation, and chlorhexidine gluconate brushing) might enhance the identification, disruption, and finally removal of the bacterial biofilm, which is the main responsible of antibiotics and antibodies resistance. The DAPRI technique might represent a safe and more conservative treatment for acute and early hematogenous periprosthetic joint infection.Entities:
Keywords: DAIR; DAPRI; PJI; TKA; infection
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Year: 2019 PMID: 31554470 DOI: 10.1177/2309499019874413
Source DB: PubMed Journal: J Orthop Surg (Hong Kong) ISSN: 1022-5536 Impact factor: 1.118