Literature DB >> 31544730

Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development from Infancy to Emerging Adulthood.

Kaili Rimfeld1, Margherita Malanchini1,2, Thomas Spargo1, Gemma Spickernell1, Saskia Selzam1, Andrew McMillan1, Philip S Dale3, Thalia C Eley1, Robert Plomin1.   

Abstract

The Twins Early Development Study (TEDS) is a longitudinal twin study that recruited over 16,000 twin-pairs born between 1994 and 1996 in England and Wales through national birth records. More than 10,000 of these families are still engaged in the study. TEDS was and still is a representative sample of the population in England and Wales. Rich cognitive and emotional/behavioral data have been collected from the twins from infancy to emerging adulthood, with data collection at first contact and at ages 2, 3, 4, 7, 8, 9, 10, 12, 14, 16, 18 and 21, enabling longitudinal genetically sensitive analyses. Data have been collected from the twins themselves, from their parents and teachers, and from the UK National Pupil Database. Genotyped DNA data are available for 10,346 individuals (who are unrelated except for 3320 dizygotic co-twins). TEDS data have contributed to over 400 scientific papers involving more than 140 researchers in 50 research institutions. TEDS offers an outstanding resource for investigating cognitive and behavioral development across childhood and early adulthood and actively fosters scientific collaborations.

Entities:  

Keywords:  TEDS; behavioral genetics; environment; genetics; genomics; longitudinal; twin studies

Year:  2019        PMID: 31544730      PMCID: PMC7056571          DOI: 10.1017/thg.2019.56

Source DB:  PubMed          Journal:  Twin Res Hum Genet        ISSN: 1832-4274            Impact factor:   1.587


  30 in total

1.  Genetic and environmental mediation of the relationship between language and nonverbal impairment in 4-year-old twins.

Authors:  Essi Viding; Thomas S Price; Frank M Spinath; Dorothy V M Bishop; Philip S Dale; Robert Plomin
Journal:  J Speech Lang Hear Res       Date:  2003-12       Impact factor: 2.297

2.  The structure of language abilities at 4 years: a twin study.

Authors:  Essi Colledge; Dorothy V M Bishop; Gesina Koeppen-Schomerus; Thomas S Price; Francesca G E Happé; Thalia C Eley; Philip S Dale; Robert Plomin
Journal:  Dev Psychol       Date:  2002-09

3.  Polygenic score for educational attainment captures DNA variants shared between personality traits and educational achievement.

Authors:  Emily Smith-Woolley; Saskia Selzam; Robert Plomin
Journal:  J Pers Soc Psychol       Date:  2019-03-28

4.  The phenotypic and genetic structure of depression and anxiety disorder symptoms in childhood, adolescence, and young adulthood.

Authors:  Monika A Waszczuk; Helena M S Zavos; Alice M Gregory; Thalia C Eley
Journal:  JAMA Psychiatry       Date:  2014-08       Impact factor: 21.596

5.  Genetic and environmental influences on adolescent attachment.

Authors:  Pasco Fearon; Yael Shmueli-Goetz; Essi Viding; Peter Fonagy; Robert Plomin
Journal:  J Child Psychol Psychiatry       Date:  2013-11-21       Impact factor: 8.982

6.  Heritability of Intraindividual Mean and Variability of Positive and Negative Affect.

Authors:  Yao Zheng; Robert Plomin; Sophie von Stumm
Journal:  Psychol Sci       Date:  2016-10-13

7.  The genetic and environmental origins of learning abilities and disabilities in the early school years.

Authors:  Yulia Kovas; Claire M A Haworth; Philip S Dale; Robert Plomin
Journal:  Monogr Soc Res Child Dev       Date:  2007

8.  Twins' Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence.

Authors:  Bonamy R Oliver; Robert Plomin
Journal:  Twin Res Hum Genet       Date:  2007-02       Impact factor: 1.587

9.  Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood.

Authors:  Claire M A Haworth; Oliver S P Davis; Robert Plomin
Journal:  Twin Res Hum Genet       Date:  2012-10-30       Impact factor: 1.587

10.  A polygenic p factor for major psychiatric disorders.

Authors:  Saskia Selzam; Jonathan R I Coleman; Avshalom Caspi; Terrie E Moffitt; Robert Plomin
Journal:  Transl Psychiatry       Date:  2018-10-02       Impact factor: 6.222

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  22 in total

1.  Does the Inclusion of a Genome-Wide Polygenic Score Improve Early Risk Prediction for Later Language and Literacy Delay?

Authors:  Philip S Dale; Sophie von Stumm; Saskia Selzam; Marianna E Hayiou-Thomas
Journal:  J Speech Lang Hear Res       Date:  2020-04-28       Impact factor: 2.297

2.  Is quality of life related to high autistic traits, high ADHD traits and their Interaction? Evidence from a Young-Adult Community-Based twin sample.

Authors:  Simone J Capp; Jessica Agnew-Blais; Alex Lau-Zhu; Emma Colvert; Charlotte Tye; Ümit Aydin; Alexandra Lautarescu; Claire Ellis; Tyler Saunders; Lucy O'Brien; Angelica Ronald; Francesca Happé; Gráinne McLoughlin
Journal:  J Autism Dev Disord       Date:  2022-07-08

3.  Investigating the causal risk factors for self-harm by integrating Mendelian randomisation within twin modelling.

Authors:  Kai Xiang Lim; Olakunle Ayokunmi Oginni; Kaili Rimfeld; Jean-Baptiste Pingault; Frühling Rijsdijk
Journal:  Behav Genet       Date:  2022-09-14       Impact factor: 2.965

4.  Children of the Twins Early Development Study (CoTEDS): A Children-of-Twins Study.

Authors:  Yasmin I Ahmadzadeh; Thalia C Eley; Robert Plomin; Philip S Dale; Kathryn J Lester; Bonamy R Oliver; Andrew McMillan; Tom A McAdams
Journal:  Twin Res Hum Genet       Date:  2019-09-09       Impact factor: 1.587

Review 5.  Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology.

Authors:  Monika A Waszczuk; Nicholas R Eaton; Robert F Krueger; Alexander J Shackman; Irwin D Waldman; David H Zald; Benjamin B Lahey; Christopher J Patrick; Christopher C Conway; Johan Ormel; Steven E Hyman; Eiko I Fried; Miriam K Forbes; Anna R Docherty; Robert R Althoff; Bo Bach; Michael Chmielewski; Colin G DeYoung; Kelsie T Forbush; Michael Hallquist; Christopher J Hopwood; Masha Y Ivanova; Katherine G Jonas; Robert D Latzman; Kristian E Markon; Stephanie N Mullins-Sweatt; Aaron L Pincus; Ulrich Reininghaus; Susan C South; Jennifer L Tackett; David Watson; Aidan G C Wright; Roman Kotov
Journal:  J Abnorm Psychol       Date:  2019-12-05

6.  Evaluation of polygenic prediction methodology within a reference-standardized framework.

Authors:  Oliver Pain; Kylie P Glanville; Saskia P Hagenaars; Saskia Selzam; Anna E Fürtjes; Héléna A Gaspar; Jonathan R I Coleman; Kaili Rimfeld; Gerome Breen; Robert Plomin; Lasse Folkersen; Cathryn M Lewis
Journal:  PLoS Genet       Date:  2021-05-04       Impact factor: 5.917

7.  Why do depression, conduct, and hyperactivity symptoms co-occur across adolescence? The role of stable and dynamic genetic and environmental influences.

Authors:  Monika A Waszczuk; Helena M S Zavos; Thalia C Eley
Journal:  Eur Child Adolesc Psychiatry       Date:  2020-04-06       Impact factor: 4.785

8.  School quality ratings are weak predictors of students' achievement and well-being.

Authors:  Sophie von Stumm; Emily Smith-Woolley; Rosa Cheesman; Jean-Baptiste Pingault; Kathryn Asbury; Philip S Dale; Rebecca Allen; Yulia Kovas; Robert Plomin
Journal:  J Child Psychol Psychiatry       Date:  2020-06-02       Impact factor: 8.982

9.  Imputed gene expression risk scores: a functionally informed component of polygenic risk.

Authors:  Oliver Pain; Kylie P Glanville; Saskia Hagenaars; Saskia Selzam; Anna Fürtjes; Jonathan R I Coleman; Kaili Rimfeld; Gerome Breen; Lasse Folkersen; Cathryn M Lewis
Journal:  Hum Mol Genet       Date:  2021-05-17       Impact factor: 6.150

10.  Greater genetic risk for adult psychiatric diseases increases vulnerability to adverse outcome after preterm birth.

Authors:  Harriet Cullen; Saskia Selzam; Konstantina Dimitrakopoulou; Robert Plomin; A David Edwards
Journal:  Sci Rep       Date:  2021-06-01       Impact factor: 4.379

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