Literature DB >> 31538524

A primer of deuterium in drug design.

Sarah Cargnin1, Marta Serafini1, Tracey Pirali1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2019        PMID： 31538524     DOI： 10.4155/fmc-2019-0183

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


× No keyword cloud information.
  11 in total

1.  Deaminative Reductive Methylation of Alkylpyridinium Salts.

Authors:  Olivia P Bercher; Shane Plunkett; Thomas E Mortimer; Mary P Watson
Journal:  Org Lett       Date:  2021-08-31       Impact factor: 6.072

2.  Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.

Authors:  Andreea L Turcu; Júlia Companys-Alemany; Matthew B Phillips; Dhilon S Patel; Christian Griñán-Ferré; M Isabel Loza; José M Brea; Belén Pérez; David Soto; Francesc X Sureda; Maria G Kurnikova; Jon W Johnson; Mercè Pallàs; Santiago Vázquez
Journal:  Eur J Med Chem       Date:  2022-04-08       Impact factor: 7.088

3.  Synthesis and anti-SARS-CoV-2 activity of deuterated GS-441524 analogs.

Authors:  Wei Zheng; Tianwen Hu; Yumin Zhang; Daibao Wei; Yuanchao Xie; Jingshan Shen
Journal:  Tetrahedron Lett       Date:  2022-07-09       Impact factor: 2.032

4.  Rational deuteration of dronedarone attenuates its toxicity in human hepatic HepG2 cells.

Authors:  Lloyd Wei Tat Tang; Royden Yu Ren Lim; Gopalakrishnan Venkatesan; Eric Chun Yong Chan
Journal:  Toxicol Res (Camb)       Date:  2022-03-28       Impact factor: 2.680

5.  Synthesis of xanthohumol and xanthohumol-d3 from naringenin.

Authors:  Joanna Andrusiak; Kinga Mylkie; Małgorzata Wysocka; Jacek Ścianowski; Andrzej Wolan; Marcin Budny
Journal:  RSC Adv       Date:  2021-08-31       Impact factor: 4.036

6.  Hybrid Chemo-, Bio-, and Electrocatalysis for Atom-Efficient Deuteration of Cofactors in Heavy Water.

Authors:  Jack S Rowbotham; Holly A Reeve; Kylie A Vincent
Journal:  ACS Catal       Date:  2021-02-11       Impact factor: 13.084

7.  An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline.

Authors:  Silvio Aprile; Giorgia Colombo; Marta Serafini; Rosanna Di Paola; Federica Pisati; Irene Preet Bhela; Salvatore Cuzzocrea; Giorgio Grosa; Tracey Pirali
Journal:  ACS Med Chem Lett       Date:  2022-07-14       Impact factor: 4.632

8.  Cultivation of the microalgae Chlamydomonas reinhardtii and Desmodesmus quadricauda in highly deuterated media: Balancing the light intensity.

Authors:  Veronika Kselíková; Kamila Husarčíková; Peter Mojzeš; Vilém Zachleder; Kateřina Bišová
Journal:  Front Bioeng Biotechnol       Date:  2022-09-05

9.  Titanocene(III)-Catalyzed Precision Deuteration of Epoxides.

Authors:  Dina Schwarz G Henriques; Elena Rojo-Wiechel; Sven Klare; Regine Mika; Sebastian Höthker; Jonathan H Schacht; Niklas Schmickler; Andreas Gansäuer
Journal:  Angew Chem Int Ed Engl       Date:  2021-12-21       Impact factor: 16.823

10.  Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease.

Authors:  Chamandi S Dampalla; Yunjeong Kim; Naemi Bickmeier; Athri D Rathnayake; Harry Nhat Nguyen; Jian Zheng; Maithri M Kashipathy; Matthew A Baird; Kevin P Battaile; Scott Lovell; Stanley Perlman; Kyeong-Ok Chang; William C Groutas
Journal:  J Med Chem       Date:  2021-07-02       Impact factor: 7.446
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.