Roberto Luigi Cazzato1, Pierre De Marini2, Loïc Leclerc2, Danoob Dalili3,4, Guillaume Koch2, Pramod Rao2, Pierre Auloge2, Julien Garnon2, Afshin Gangi2. 1. Service d'Imagerie Interventionnelle, Hôpitaux Universitaires de Strasbourg, 1, place de l'hopital, 67000, Strasbourg, France. roberto-luigi.cazzato@chru-strasbourg.fr. 2. Service d'Imagerie Interventionnelle, Hôpitaux Universitaires de Strasbourg, 1, place de l'hopital, 67000, Strasbourg, France. 3. Department of Diagnostic and Interventional Radiology, Guy's and St. Thomas' Hospitals NHS Foundation Trust, London, UK. 4. Section of Musculoskeletal Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Abstract
AIM: To investigate the shape and the volume of ablation zones obtained with microwave ablation (MWA) performed with multiple antennas in liver tumours. MATERIALS AND METHODS: Tumour volume, number of antennas, size (long diameter (Dl), along the antenna axis; short diameter (Ds), perpendicular to the antenna axis; vertical diameter (Dv), vertical to both Dl and Ds) and shape (roundness index (RI); 1 corresponds to a sphere) of the ablation zone, ablation volume, and complications were evaluated. RESULTS: Mean Dl, Ds, and Dv were 4.7 ± 1.4 cm, 3.9 ± 1.4 cm, and 3.8 ± 1.0 cm, respectively. Mean RIs (Ds/Dl, Dv/Dl, and Dv/Ds) were 0.83 ± 0.13, 0.83 ± 0.17, and 1.02 ± 0.23, respectively, without any difference between the mean RI obtained with the double (0.84 ± 0.01) and that with the triple-antenna (0.93 ± 0.13) approach (p = 0.25). Mean ablation volume was 41 ± 32 cm3 (vs. mean tumour volume 13 ± 10 cm3; range 1-40; p < 0.001). No complications were noted. CONCLUSIONS: Simultaneous multi-antenna MWA of liver tumours results in large nearly spherical ablation zones. KEY POINTS: • Simultaneous multi-antenna microwave ablation of liver tumours results in nearly spherical ablation zones. • The multi-antenna approach generates oversized ablation volumes compared with the target tumour volume. • The multi-antenna approach is safe.
AIM: To investigate the shape and the volume of ablation zones obtained with microwave ablation (MWA) performed with multiple antennas in liver tumours. MATERIALS AND METHODS:Tumour volume, number of antennas, size (long diameter (Dl), along the antenna axis; short diameter (Ds), perpendicular to the antenna axis; vertical diameter (Dv), vertical to both Dl and Ds) and shape (roundness index (RI); 1 corresponds to a sphere) of the ablation zone, ablation volume, and complications were evaluated. RESULTS: Mean Dl, Ds, and Dv were 4.7 ± 1.4 cm, 3.9 ± 1.4 cm, and 3.8 ± 1.0 cm, respectively. Mean RIs (Ds/Dl, Dv/Dl, and Dv/Ds) were 0.83 ± 0.13, 0.83 ± 0.17, and 1.02 ± 0.23, respectively, without any difference between the mean RI obtained with the double (0.84 ± 0.01) and that with the triple-antenna (0.93 ± 0.13) approach (p = 0.25). Mean ablation volume was 41 ± 32 cm3 (vs. mean tumour volume 13 ± 10 cm3; range 1-40; p < 0.001). No complications were noted. CONCLUSIONS: Simultaneous multi-antenna MWA of liver tumours results in large nearly spherical ablation zones. KEY POINTS: • Simultaneous multi-antenna microwave ablation of liver tumours results in nearly spherical ablation zones. • The multi-antenna approach generates oversized ablation volumes compared with the target tumour volume. • The multi-antenna approach is safe.
Authors: Thomas J Vogl; Lajos M Basten; Nour-Eldin A Nour-Eldin; Benjamin Kaltenbach; Boris Bodelle; Julian L Wichmann; Hanns Ackermann; Nagy N N Naguib Journal: Int J Hyperthermia Date: 2017-08-03 Impact factor: 3.914
Authors: Colin M Harari; Michelle Magagna; Mariajose Bedoya; Fred T Lee; Meghan G Lubner; J Louis Hinshaw; Timothy Ziemlewicz; Christopher L Brace Journal: Radiology Date: 2015-07-02 Impact factor: 11.105
Authors: P Saccomandi; E Schena; C Massaroni; Y Fong; R F Grasso; F Giurazza; B Beomonte Zobel; X Buy; J Palussiere; R L Cazzato Journal: Eur J Surg Oncol Date: 2015-09-25 Impact factor: 4.424
Authors: Timothy J Ziemlewicz; J Louis Hinshaw; Meghan G Lubner; Christopher L Brace; Marci L Alexander; Parul Agarwal; Fred T Lee Journal: J Vasc Interv Radiol Date: 2014-11-04 Impact factor: 3.464
Authors: Ryan T Groeschl; Charles H C Pilgrim; Erin M Hanna; Kerri A Simo; Ryan Z Swan; David Sindram; John B Martinie; David A Iannitti; Mark Bloomston; Carl Schmidt; Hooman Khabiri; Lawrence A Shirley; Robert C G Martin; Susan Tsai; Kiran K Turaga; Kathleen K Christians; William S Rilling; T Clark Gamblin Journal: Ann Surg Date: 2014-06 Impact factor: 12.969